iPTMnet Report for P04066 (FUCA1)


Protein Information

Cytoscape View


UniProt AC / UniProt ID P04066 / FUCO_HUMAN
Protein Name Tissue alpha-L-fucosidase precursor
Gene Name Name: FUCA1
ORFNames:Nbla10230;
Organism Homo sapiens (Human)

PRO ID PR:P04066
DAG View
PRO Name tissue alpha-L-fucosidase (human)
Definition A tissue alpha-L-fucosidase that is encoded in the genome of human.
Short Label hFUCA1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P04066 (FUCA1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K137 Sumoylation PhosphoSitePlus
T170 Phosphorylation PhosphoSitePlus   UniProt 21406692
Y182 Phosphorylation PhosphoSitePlus
N241 N-Glycosylation GlyGen   UniProt 19159218
N268 N-Glycosylation GlyGen 23090970, 29741879, 32125861, ...24190977
S270 O-Glycosylation GlyGen 22661428
N382 N-Glycosylation GlyGen   UniProt 23090970, 29741879, 19159218, ...24190977
T383 O-Glycosylation GlyGen 28657654, 34725712, 22661428, ...35254053


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S270 F270 Biomuta DOID:4159 / skin cancer [ cosmic ]
T383 K383 Biomuta DOID:10534 / stomach cancer [ cosmic ]