iPTMnet Report for P04053 (DNTT)


Protein Information

Cytoscape View


UniProt AC / UniProt ID P04053 / TDT_HUMAN
Protein Name DNA nucleotidylexotransferase
Gene Name Name: DNTT
Synonyms:TDT;
Organism Homo sapiens (Human)

PRO ID PR:P04053
DAG View
PRO Name DNA nucleotidylexotransferase (human)
Definition A DNA nucleotidylexotransferase that is encoded in the genome of human.
Short Label hDNTT
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P04053 (DNTT) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S10 Phosphorylation PhosphoSitePlus
K122 Ubiquitination PhosphoSitePlus
S132 Phosphorylation PhosphoSitePlus
T135 Phosphorylation PhosphoSitePlus
T142 Phosphorylation PhosphoSitePlus
K149 Ubiquitination PhosphoSitePlus
K199 Ubiquitination PhosphoSitePlus
K209 Ubiquitination PhosphoSitePlus
K220 Ubiquitination PhosphoSitePlus
K222 Ubiquitination PhosphoSitePlus
K238 Ubiquitination PhosphoSitePlus
K250 Ubiquitination PhosphoSitePlus
K261 Ubiquitination PhosphoSitePlus
K265 Ubiquitination PhosphoSitePlus
K290 Ubiquitination PhosphoSitePlus
K316 Acetylation PhosphoSitePlus
K339 Ubiquitination PhosphoSitePlus
K363 Ubiquitination PhosphoSitePlus
K370 Ubiquitination PhosphoSitePlus
K371 Ubiquitination PhosphoSitePlus
S382 Phosphorylation PhosphoSitePlus
T383 Phosphorylation PhosphoSitePlus
K393 Ubiquitination PhosphoSitePlus
K402 Ubiquitination PhosphoSitePlus
K408 Ubiquitination PhosphoSitePlus
K425 Ubiquitination PhosphoSitePlus
K468 Ubiquitination PhosphoSitePlus
Y477 Phosphorylation PhosphoSitePlus
K479 Ubiquitination PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
Y477 Phosphorylation HPRD 18491316
Site PTM Type PTM Enzyme Score Source PMID
Y476 Phosphorylation HPRD 18491316


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S10 R10 Biomuta DOID:3571 / liver cancer [ cosmic ]
K209 N209 Biomuta DOID:4362 / cervical cancer [ cosmic ]
K238 N238 Biomuta DOID:2394 / ovarian cancer [ cosmic, icgc ]
K261 N261 Biomuta DOID:363 / uterine cancer [ icgc ]
K370 N370 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
K408 R408 Biomuta DOID:1319 / brain cancer [ cosmic ]
K425 N425 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ]
K425 E425 Biomuta DOID:10534 / stomach cancer [ cosmic ]
K468 N468 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ]
K479 N479 Biomuta DOID:363 / uterine cancer [ icgc ] DOID:1324 / lung cancer [ cosmic, icgc ]