Protein Information

Cytoscape View


UniProt AC / UniProt ID P04004 / VTNC_HUMAN
Protein Name Vitronectin precursor
Gene Name Name: VTN
Organism Homo sapiens (Human)

PRO ID PR:P04004
DAG View
PRO Name vitronectin (human)
Definition A vitronectin that is encoded in the genome of human.
Short Label hVTN
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P04004 (VTN) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
T69 Phosphorylation P68400 (CSNK2A1) HPRD   phospho.ELM   PhosphoSitePlus   UniProt 9733784
Y75 Phosphorylation PhosphoSitePlus
T76 Phosphorylation P68400 (CSNK2A1) HPRD   phospho.ELM   PhosphoSitePlus   UniProt 9733784
N86 N-Glycosylation UniProt 16335952, 19139490, 14760718, ...17558413, 19159218
S106 Phosphorylation PhosphoSitePlus
S130 Phosphorylation PhosphoSitePlus   UniProt 24275569
S137 Phosphorylation PhosphoSitePlus   UniProt 24275569
T141 Phosphorylation PhosphoSitePlus
N169 N-Glycosylation UniProt 16335952, 14760718, 19159218
S171 Phosphorylation HPRD   phospho.ELM 17081983
Y179 Phosphorylation PhosphoSitePlus
K218 Acetylation PhosphoSitePlus
T219 Phosphorylation PhosphoSitePlus
N242 N-Glycosylation UniProt 16335952, 19139490, 14760718, ...19159218
S312 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 19824718, 18088087, 16807684, ...17558413, 24275569
T325 Phosphorylation PhosphoSitePlus
S357 Phosphorylation PhosphoSitePlus
S364 Phosphorylation PhosphoSitePlus
S381 Phosphorylation P05771 (PRKCB) , P17252 (PRKCA) , P05129 (PRKCG) HPRD   PhosphoSitePlus 9030777
S386 Phosphorylation P17252 (PRKCA) PhosphoSitePlus 9030777
S393 Phosphorylation P17252 (PRKCA) PhosphoSitePlus 9030777
S397 Phosphorylation P17252 (PRKCA) , P17612 (PRKACA) HPRD   phospho.ELM   PhosphoSitePlus   UniProt 11795878, 2448300, 9030777, ...1696913, 1706595, 11034322
S406 Phosphorylation PhosphoSitePlus
S407 Phosphorylation PhosphoSitePlus
Y420 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S137 P137 Biomuta DOID:1324 / lung cancer [ tcga ]
S137 * Biomuta DOID:11054 / urinary bladder cancer [ cosmic, icgc, tcga ]