iPTMnet Report for P04003 (C4BPA)


Protein Information

Cytoscape View


UniProt AC / UniProt ID P04003 / C4BPA_HUMAN
Protein Name C4b-binding protein alpha chain precursor
Gene Name Name: C4BPA
Synonyms:C4BP;
Organism Homo sapiens (Human)

PRO ID PR:P04003
DAG View
PRO Name C4b-binding protein alpha chain (human)
Definition A C4b-binding protein alpha chain that is encoded in the genome of human.
Short Label hC4BPA
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P04003 (C4BPA) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
T55 O-Glycosylation GlyGen 30459171
S57 O-Glycosylation GlyGen 30459171
S187 Phosphorylation PhosphoSitePlus
N221 N-Glycosylation GlyGen   UniProt 16335952, 19159218, 23090970, ...3840370, 29741879, 29671580
S230 O-Glycosylation GlyGen 30459171
T317 O-Glycosylation GlyGen 30459171
T340 O-Glycosylation GlyGen 30459171
N385 N-Glycosylation GlyGen 23090970
S469 Phosphorylation PhosphoSitePlus
Y470 Phosphorylation PhosphoSitePlus
S471 Phosphorylation PhosphoSitePlus
S474 Phosphorylation PhosphoSitePlus
S495 Phosphorylation PhosphoSitePlus
N506 N-Glycosylation GlyGen   UniProt 16335952, 19159218, 23090970, ...14760718, 3840370, 29741879, 29671580
N528 N-Glycosylation GlyGen   UniProt 23090970, 14760718, 3840370
Site PTM Type PTM Enzyme Score Source PMID
N221 N-Glycosylation PRO 29671580
N506 N-Glycosylation PRO 29671580


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S57 L57 Biomuta DOID:4159 / skin cancer [ cosmic ]
T317 A317 Biomuta DOID:8618 / oral cavity cancer [ cosmic ] DOID:11934 / head and neck cancer [ icgc ]
T340 I340 Biomuta DOID:2531 / hematologic cancer [ cosmic ]
N528 S528 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
N528 K528 Biomuta DOID:4159 / skin cancer [ cosmic ]
N528 D528 Biomuta DOID:4159 / skin cancer [ cosmic ]