Protein Information

Cytoscape View


UniProt AC / UniProt ID P02795 / MT2_HUMAN
Protein Name Metallothionein-2
Gene Name Name: MT2A
Synonyms:CES1,MT2;
Organism Homo sapiens (Human)

PRO ID PR:P02795
DAG View
PRO Name metallothionein-2 (human)
Definition A metallothionein-2 that is encoded in the genome of human.
Short Label hMT2A
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P02795 (MT2A) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
M1 Acetylation PRO   UniProt 19413330
S6 Phosphorylation HPRD   PhosphoSitePlus 18491316
S12 Phosphorylation PhosphoSitePlus
T14 Phosphorylation PhosphoSitePlus
S18 Phosphorylation PhosphoSitePlus
K22 Acetylation PhosphoSitePlus
S32 Phosphorylation PhosphoSitePlus
S35 Phosphorylation PhosphoSitePlus
K43 Ubiquitination PhosphoSitePlus
K51 Acetylation PhosphoSitePlus
K51 Ubiquitination PhosphoSitePlus
K56 Ubiquitination PhosphoSitePlus
S58 Phosphorylation PhosphoSitePlus   UniProt 24275569


Proteoforms

PRO ID (Short Label) Sites PTM Enzyme Source PMID
PR:000036277 (hMT2A/Ac:1) acM1 PRO


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
M1 I1 Biomuta DOID:3571 / liver cancer [ icgc ] DOID:0070003 / blastoma [ cosmic ]
M1 K1 Biomuta DOID:1324 / lung cancer [ cosmic ]
S6 Y6 Biomuta DOID:1909 / melanoma [ icgc, tcga ]
S6 F6 Biomuta DOID:1612 / breast cancer [ tcga ]
T14 I14 Biomuta DOID:363 / uterine cancer [ cosmic, icgc, tcga ]