iPTMnet Report for P02795 (MT2A)
Protein Information
UniProt AC / UniProt ID | P02795 / MT2_HUMAN |
Protein Name | Metallothionein-2 |
Gene Name | Name: MT2A Synonyms:CES1,MT2; |
Organism | Homo sapiens (Human) |
PRO ID | PR:P02795 |
PRO Name | metallothionein-2 (human) |
Definition | A metallothionein-2 that is encoded in the genome of human. |
Short Label | hMT2A |
Category | organism-gene |
P02795 (MT2A) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
M1 | Acetylation | score2 | PRO UniProt | 19413330 | ||
S6 | Phosphorylation | score2 | HPRD PhosphoSitePlus | 18491316 | ||
S12 | Phosphorylation | score1 | PhosphoSitePlus | |||
T14 | Phosphorylation | score1 | PhosphoSitePlus | |||
S18 | Phosphorylation | score1 | PhosphoSitePlus | |||
K22 | Acetylation | score1 | PhosphoSitePlus | |||
S32 | Phosphorylation | score1 | PhosphoSitePlus | |||
S35 | Phosphorylation | score1 | PhosphoSitePlus | |||
K43 | Ubiquitination | score1 | PhosphoSitePlus | |||
K51 | Acetylation | score1 | PhosphoSitePlus | |||
K51 | Ubiquitination | score1 | PhosphoSitePlus | |||
K56 | Ubiquitination | score1 | PhosphoSitePlus | |||
S58 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 24275569 |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
S6 | Y6 | Biomuta | DOID:4159 / skin cancer [ cosmic, icgc ] | |
S6 | F6 | Biomuta | DOID:1612 / breast cancer [ cosmic, icgc ] DOID:11054 / urinary bladder cancer [ cosmic ] | |
T14 | I14 | Biomuta | DOID:363 / uterine cancer [ cosmic, icgc ] |