iPTMnet Report for P02794 (FTH1)


Protein Information

Cytoscape View


UniProt AC / UniProt ID P02794 / FRIH_HUMAN
Protein Name Ferritin heavy chain
Gene Name Name: FTH1
Synonyms:FTH,FTHL6;ORFNames:OK/SW-cl.84,PIG15;
Organism Homo sapiens (Human)

PRO ID PR:P02794
DAG View
PRO Name ferritin heavy chain (human)
Definition A ferritin heavy chain that is encoded in the genome of human.
Short Label hFTH1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P02794 (FTH1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
M1 Acetylation UniProt 22814378
T2 Acetylation UniProt 22814378
T6 Phosphorylation HPRD   PhosphoSitePlus 19651622
S7 Phosphorylation HPRD   PhosphoSitePlus 19651622
Y13 Phosphorylation PhosphoSitePlus
S17 O-Glycosylation GlyGen 33465208
K54 Ubiquitination PhosphoSitePlus
K69 Ubiquitination PhosphoSitePlus
K72 Sumoylation PhosphoSitePlus
K72 Ubiquitination PhosphoSitePlus
K88 Ubiquitination PhosphoSitePlus
S96 Phosphorylation PhosphoSitePlus
C103 Methylation IEDB 31844290
K109 Ubiquitination PhosphoSitePlus
N112 N-Glycosylation GlyGen 24190977
S114 Phosphorylation PhosphoSitePlus
K120 Ubiquitination PhosphoSitePlus
K125 Ubiquitination PhosphoSitePlus
K144 Ubiquitination PhosphoSitePlus
K147 Ubiquitination PhosphoSitePlus
K158 Ubiquitination PhosphoSitePlus
S164 Phosphorylation HPRD   PhosphoSitePlus 17081983, 20068231, 20230923
Y169 Phosphorylation HPRD   PhosphoSitePlus 17081983
T175 Phosphorylation HPRD   PhosphoSitePlus 19651622, 20166139, 20068231, ...20230923
S179 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 21406692, 17287340, 16964243, ...20230923, 15302935, 18452278, 19651622, 18669648, 24275569, 20166139, 18318008, 20068231, 17081983
S183 Phosphorylation HPRD   PhosphoSitePlus   UniProt 17081983, 20230923, 18452278, ...19651622, 18669648, 20166139, 18318008, 20068231


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
T6 S6 Biomuta DOID:4606 / bile duct cancer [ cosmic ]
K54 R54 Biomuta DOID:1793 / pancreatic cancer [ cosmic ] DOID:2531 / hematologic cancer [ cosmic ]
S96 R96 Biomuta DOID:4606 / bile duct cancer [ cosmic ]
S96 I96 Biomuta DOID:10534 / stomach cancer [ cosmic ]
S114 L114 Biomuta DOID:4159 / skin cancer [ cosmic ]
K144 E144 Biomuta DOID:2394 / ovarian cancer [ cosmic ]
K144 R144 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
T175 I175 Biomuta DOID:4159 / skin cancer [ cosmic ]
S183 N183 Biomuta DOID:4159 / skin cancer [ cosmic ]