iPTMnet Report for P02774 (GC)
Protein Information
| UniProt AC / UniProt ID | P02774 / VTDB_HUMAN |
| Protein Name | Vitamin D-binding protein precursor |
| Gene Name | Name: GC |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:P02774 |
| PRO Name | vitamin D-binding protein (human) |
| Definition | A vitamin D-binding protein that is encoded in the genome of human. |
| Short Label | hGC |
| Category | organism-gene |
P02774 (GC) as Substrate
| Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
|---|---|---|---|---|---|---|
| S42 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S95 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y155 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S210 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T213 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T214 | Phosphorylation | score1 | PhosphoSitePlus | |||
| C220 | Methylation | score1 | IEDB | 31844290 | ||
| N288 | N-Glycosylation | score1 | GlyGen | 29671580 | ||
| K419 | Acetylation | score1 | PhosphoSitePlus | |||
| N451 | N-Glycosylation | score1 | GlyGen | 23090970 |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| S95 | F95 | Biomuta | DOID:4159 / skin cancer [ cosmic ] | |
| T214 | I214 | Biomuta | DOID:363 / uterine cancer [ icgc ] | |
| C220 | R220 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
| N288 | D288 | Biomuta | DOID:1324 / lung cancer [ cosmic ] | |
| K419 | T419 | Biomuta | DOID:10534 / stomach cancer [ cosmic, icgc ] |
DAG View