Protein Information

Cytoscape View

UniProt AC / UniProt ID P02771 / FETA_HUMAN
Protein Name Alpha-fetoprotein precursor
Gene Name Name: AFP
Organism Homo sapiens (Human)

PRO ID PR:P02771
DAG View
PRO Name alpha-fetoprotein (human)
Definition An alpha-fetoprotein that is encoded in the genome of human.
Short Label hAFP
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species

P02771 (AFP) as Substrate

Site PTM Type PTM Enzyme Score Source PMID
S111 Phosphorylation UniProt 26091039
S115 Phosphorylation UniProt 26091039
S117 Phosphorylation UniProt 26091039
N197 N-Glycosylation GlyGen 23345538
K228 Acetylation PhosphoSitePlus
T248 Phosphorylation PhosphoSitePlus
N251 N-Glycosylation GlyGen 6192908, 7679920, 1694115, ...7686446, 7511099
S344 Phosphorylation UniProt 26091039
S368 Phosphorylation PhosphoSitePlus
Y377 Phosphorylation PhosphoSitePlus
Y404 Phosphorylation PhosphoSitePlus
S408 Phosphorylation PhosphoSitePlus
K413 Acetylation PhosphoSitePlus
S415 Phosphorylation PhosphoSitePlus
S444 Phosphorylation UniProt 26091039
S445 Phosphorylation UniProt 26091039

PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S115 I115 Biomuta DOID:3571 / liver cancer [ icgc ]
S368 P368 Biomuta DOID:363 / uterine cancer [ tcga ]
S408 I408 Biomuta DOID:3571 / liver cancer [ icgc ]
S445 P445 Biomuta DOID:363 / uterine cancer [ tcga ]