iPTMnet Report for P02766 (TTR)
Protein Information
| UniProt AC / UniProt ID | P02766 / TTHY_HUMAN |
| Protein Name | Transthyretin precursor |
| Gene Name | Name: TTR Synonyms:PALB; |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:P02766 |
| PRO Name | transthyretin (human) |
| Definition | A transthyretin that is encoded in the genome of human. |
| Short Label | hTTR |
| Category | organism-gene |
DAG ViewP02766 (TTR) as Substrate
 |
Site | PTM Type | PTM Enzyme | Score | Source | PMID |
|---|---|---|---|---|---|---|
| C10 | S-Nitrosylation | score2 | dbSNO | 16101296, 22178444 | ||
| T23 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T25 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S72 | Phosphorylation | score1 | PhosphoSitePlus | |||
| N118 | N-Glycosylation | score4 | GlyGen UniProt | 16335952, 19167329 | ||
| Y125 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S137 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T138 | Phosphorylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| Y125 | H125 | Biomuta | [ cosmic ] DOID:1324 / lung cancer [ cosmic, icgc ] | |
| T138 | A138 | Biomuta | DOID:363 / uterine cancer [ icgc ] |
