iPTMnet Report for P02765 (AHSG)


Protein Information

Cytoscape View


UniProt AC / UniProt ID P02765 / FETUA_HUMAN
Protein Name Alpha-2-HS-glycoprotein precursor
Gene Name Name: AHSG
Synonyms:FETUA;ORFNames:PRO2743;
Organism Homo sapiens (Human)

PRO ID PR:P02765
DAG View
PRO Name alpha-2-HS-glycoprotein (human)
Definition An alpha-2-HS-glycoprotein that is encoded in the genome of human.
Short Label hAHSG
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P02765 (AHSG) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S74 Phosphorylation PhosphoSitePlus
K131 Ubiquitination PhosphoSitePlus
S134 Phosphorylation PhosphoSitePlus   UniProt 24275569
S135 Phosphorylation HPRD   PhosphoSitePlus   UniProt 20166139, 26091039, 18212344
S138 Phosphorylation HPRD   IEDB   phospho.ELM   PhosphoSitePlus   UniProt 35494241, 18491316, 18088087, ...18212344, 19562805, 19664994, 19007248, 18318008, 18669648, 20187088, 11439093, 20166139, 23186163, 26091039, 19415658, 24275569
R143 Methylation PhosphoSitePlus
K144 Acetylation PhosphoSitePlus
N156 N-Glycosylation GlyGen 16335952, 24530628, 30237853, ...19159218, 18514042, 14760718, 22171320, 32125861, 19139490, 19838169, 6833285, 29391424, 16740002, 1457416, 29741879, 29671580, 24417605, 24841998
N176 N-Glycosylation GlyGen 16335952, 34725484, 24530628, ...30237853, 32125861, 22171320, 24417605, 19838169, 6833285, 29391424, 16740002, 1457416, 29741879, 12754519, 29671580, 29992770, 24841998
S196 O-Glycosylation GlyGen 30459171
T197 O-Glycosylation GlyGen 30459171
T202 O-Glycosylation GlyGen 30459171
K218 Acetylation IEDB 34357683
C219 Methylation IEDB 31844290
K225 Acetylation PhosphoSitePlus
K225 Ubiquitination PhosphoSitePlus
Y227 Phosphorylation PhosphoSitePlus
K231 Methylation PhosphoSitePlus
S256 O-Glycosylation GlyGen 6833285, 26598643
T270 O-Glycosylation GlyGen 30459171, 1457416, 6833285, ...24417605, 26598643
S280 O-Glycosylation GlyGen 30459171
S293 O-Glycosylation GlyGen 30459171
Y314 Phosphorylation PhosphoSitePlus
T319 Phosphorylation PhosphoSitePlus   UniProt 26091039, 24275569
S325 O-Glycosylation GlyGen 30459171
S325 Phosphorylation PhosphoSitePlus   UniProt 26091039
S328 O-Glycosylation GlyGen 30459171
S328 Phosphorylation HPRD   PhosphoSitePlus   UniProt 19824718, 26091039
S330 Phosphorylation HPRD   PhosphoSitePlus   UniProt 19824718, 11439093, 19562805, ...24275569, 26091039
S334 Phosphorylation HPRD   PhosphoSitePlus 19562805, 19824718
T341 Phosphorylation PhosphoSitePlus
S346 O-Glycosylation GlyGen   PhosphoSitePlus 30459171, 22171320, 6833285, ...1457416, 23584533, 24417605, 26598643
S346 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
N156 N-Glycosylation PRO 29671580, 19838169, 6833285, ...22171320, 24841998
N176 N-Glycosylation PRO 29671580, 19838169, 6833285, ...22171320, 24841998


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S74 F74 Biomuta DOID:11054 / urinary bladder cancer [ cosmic, icgc ]
R143 S143 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
R143 L143 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
K144 R144 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ] DOID:3571 / liver cancer [ cosmic ]
N176 D176 Biomuta DOID:10534 / stomach cancer [ cosmic ]
K218 N218 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
C219 F219 Biomuta DOID:10534 / stomach cancer [ cosmic ]
S256 T256 Biomuta DOID:9256 / colorectal cancer [ cosmic ] DOID:1324 / lung cancer [ cosmic, icgc ] DOID:1781 / thyroid gland cancer [ cosmic ] DOID:2531 / hematologic cancer [ cosmic ]
S280 F280 Biomuta DOID:4159 / skin cancer [ cosmic ] DOID:10283 / prostate cancer [ cosmic, icgc ]
T319 I319 Biomuta DOID:4159 / skin cancer [ cosmic ]
T319 N319 Biomuta DOID:1324 / lung cancer [ cosmic ]