Protein Information

Cytoscape View


UniProt AC / UniProt ID P02730 / B3AT_HUMAN
Protein Name Band 3 anion transport protein
Gene Name Name: SLC4A1
Synonyms:AE1,DI,EPB3;
Organism Homo sapiens (Human)

PRO ID PR:P02730
DAG View
PRO Name band 3 anion transport protein (human)
Definition A band 3 anion transport protein that is encoded in the genome of human.
Short Label hSLC4A1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P02730 (SLC4A1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
M1 Acetylation UniProt 701248, 2790053
Y8 Phosphorylation P43405 (SYK) , P07948 (LYN) neXtProt   phospho.ELM   PhosphoSitePlus   Signor   UniProt 10942405, 1998697, 17404032
Y21 Phosphorylation P43405 (SYK) , P07948 (LYN) neXtProt   phospho.ELM   PhosphoSitePlus   Signor   UniProt 10942405, 1998697, 17404032
S29 Phosphorylation phospho.ELM   PhosphoSitePlus 1998697
T39 Phosphorylation PhosphoSitePlus
T42 Phosphorylation P48729 (CSNK1A1) phospho.ELM   PhosphoSitePlus 9108423
T44 Phosphorylation PhosphoSitePlus
Y46 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 1998697
T48 Phosphorylation PhosphoSitePlus
T49 Phosphorylation PhosphoSitePlus
S50 Phosphorylation phospho.ELM   PhosphoSitePlus 1998697
T54 Phosphorylation PhosphoSitePlus
S162 O-Glycosylation GlyGen   PhosphoSitePlus 18984734
S181 Phosphorylation PhosphoSitePlus
S194 Phosphorylation PhosphoSitePlus
C201 S-Nitrosylation dbSNO 11890743, 22178444
S224 O-Glycosylation GlyGen   PhosphoSitePlus 18984734
S303 Phosphorylation P48729 (CSNK1A1) phospho.ELM   PhosphoSitePlus 9108423
C317 S-Nitrosylation dbSNO 11890743, 22178444
Y347 Phosphorylation PhosphoSitePlus
S349 Phosphorylation PhosphoSitePlus
S356 Phosphorylation PhosphoSitePlus
S357 Phosphorylation PhosphoSitePlus
Y359 Phosphorylation P07948 (LYN) , P43405 (SYK) IntAct   phospho.ELM   PhosphoSitePlus   RLIMS-P   UniProt 12070037, 17404032, 15649129, ...18083107, 10942405
S525 Phosphorylation PhosphoSitePlus
N642 N-Glycosylation GlyGen   UniProt 10585855, 10861210, 24121512, ...11876646, 29741879, 16096263, 10364201
S745 O-Glycosylation GlyGen   PhosphoSitePlus 18984734
K757 Ubiquitination PhosphoSitePlus
S781 Phosphorylation PhosphoSitePlus
Y818 Phosphorylation PhosphoSitePlus
T894 Phosphorylation PhosphoSitePlus
Y904 Phosphorylation P43405 (SYK) , P07948 (LYN) phospho.ELM   PhosphoSitePlus   RLIMS-P   UniProt 20980406, 17404032, 15649129, ...18083107, 10942405
Site PTM Type PTM Enzyme Score Source PMID
Y8 Phosphorylation P43405 (SYK) , P07948 (LYN) HPRD 10942405, 2065070, 1998697
Y21 Phosphorylation P43405 (SYK) , P07948 (LYN) HPRD 10942405, 2065070, 1998697
S29 Phosphorylation HPRD 1998697
T39 Phosphorylation HPRD 1998697
T42 Phosphorylation HPRD 1998697
T44 Phosphorylation HPRD 1998697
Y46 Phosphorylation HPRD 1998697
T48 Phosphorylation HPRD 1998697
T49 Phosphorylation HPRD 1998697
S50 Phosphorylation HPRD 1998697
T54 Phosphorylation HPRD 1998697
Y359 Phosphorylation P07948 (LYN) , P43405 (SYK) HPRD 10942405, 2065070
Y904 Phosphorylation P07948 (LYN) , P43405 (SYK) HPRD 10942405, 2065070


PTM-dependent PPI

PTM type Substrate Site Interactant Association type Source PMID
Phosphorylation P02730 (SLC4A1) Y359 Q06124 (PTPN11) unknown eFIP 12070037


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S29 T29 Biomuta DOID:363 / uterine cancer [ tcga ]
S162 R162 Biomuta DOID:3571 / liver cancer [ icgc ]
S303 R303 Biomuta DOID:1324 / lung cancer [ cosmic ]
Y347 F347 Biomuta DOID:3571 / liver cancer [ tcga ]
S781 F781 Biomuta DOID:3571 / liver cancer [ icgc, tcga ] DOID:0070003 / blastoma [ cosmic ]