iPTMnet Report for P02671 (FGA)


Protein Information

Cytoscape View


UniProt AC / UniProt ID P02671 / FIBA_HUMAN
Protein Name Fibrinogen alpha chain precursor
Gene Name Name: FGA
Organism Homo sapiens (Human)

PRO ID PR:P02671
DAG View
PRO Name fibrinogen alpha chain (human)
Definition A fibrinogen alpha chain that is encoded in the genome of human.
Short Label hFGA
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P02671 (FGA) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S22 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 16807684
S45 Phosphorylation PhosphoSitePlus   UniProt 26091039, 24275569
K48 Acetylation PhosphoSitePlus
S50 Phosphorylation PhosphoSitePlus   UniProt 24275569
S56 Phosphorylation PhosphoSitePlus   UniProt 26091039
K63 Acetylation PhosphoSitePlus
S91 Phosphorylation PhosphoSitePlus
Y95 Phosphorylation PhosphoSitePlus
K100 Acetylation PhosphoSitePlus
T107 O-Glycosylation GlyGen   PhosphoSitePlus 23584533
T126 Phosphorylation PhosphoSitePlus
Y127 Phosphorylation PhosphoSitePlus
K142 Acetylation PhosphoSitePlus
K167 Acetylation PhosphoSitePlus
S179 Phosphorylation PhosphoSitePlus
S185 Phosphorylation PhosphoSitePlus
K238 Acetylation PhosphoSitePlus
S239 Phosphorylation PhosphoSitePlus
T252 O-Glycosylation GlyGen   PhosphoSitePlus 23584533
T252 Phosphorylation PhosphoSitePlus
S274 Phosphorylation PhosphoSitePlus
T275 Phosphorylation PhosphoSitePlus
S276 Phosphorylation PhosphoSitePlus
Y277 Phosphorylation phospho.ELM   PhosphoSitePlus 18083107
T279 Phosphorylation PhosphoSitePlus
S281 Phosphorylation PhosphoSitePlus   UniProt 24275569
T283 O-Glycosylation GlyGen   PhosphoSitePlus 23584533
S291 Phosphorylation PhosphoSitePlus   UniProt 24275569
S294 Phosphorylation PhosphoSitePlus   UniProt 24275569
S297 O-Glycosylation GlyGen 30459171
S297 Phosphorylation PhosphoSitePlus
S300 Phosphorylation PhosphoSitePlus
T315 O-Glycosylation GlyGen 30459171
T318 O-Glycosylation GlyGen 30459171
T320 O-Glycosylation GlyGen   UniProt 30459171, 23050552
S338 O-Glycosylation GlyGen 30459171
T341 O-Glycosylation GlyGen 30459171
S351 O-Glycosylation GlyGen   UniProt 30459171, 23050552
S356 Phosphorylation PhosphoSitePlus
T357 O-Glycosylation GlyGen 30459171
T359 O-Glycosylation GlyGen 30459171
S364 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 26091039, 18088087
S365 Phosphorylation PhosphoSitePlus
S375 O-Glycosylation GlyGen 30459171
S388 Phosphorylation PhosphoSitePlus
S397 O-Glycosylation GlyGen 30459171
S397 Phosphorylation PhosphoSitePlus
S400 Phosphorylation PhosphoSitePlus
T412 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18088087, 24275569
S421 Phosphorylation PhosphoSitePlus
T424 Phosphorylation PhosphoSitePlus
T435 Phosphorylation PhosphoSitePlus
S451 Phosphorylation PhosphoSitePlus   UniProt 24275569
S453 O-Glycosylation UniProt 1675636
S460 Phosphorylation phospho.ELM 6255944
S485 Phosphorylation PhosphoSitePlus
S489 Phosphorylation PhosphoSitePlus
T499 O-Glycosylation GlyGen 30459171
T499 Phosphorylation PhosphoSitePlus
S501 O-Glycosylation GlyGen 30459171
S501 Phosphorylation PhosphoSitePlus   UniProt 24275569
T505 Phosphorylation PhosphoSitePlus   UniProt 24275569
S524 O-Glycosylation GlyGen 26598643
S524 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 26091039, 18088087
T525 O-Glycosylation GlyGen   PhosphoSitePlus 23584533, 26598643
T525 Phosphorylation PhosphoSitePlus
T528 O-Glycosylation GlyGen 30459171, 26598643
S534 O-Glycosylation GlyGen 30459171
S534 Phosphorylation PhosphoSitePlus
S542 Phosphorylation PhosphoSitePlus 3477999
S542 Phosphorylation P68400 (CSNK2A1) PhosphoSitePlus 3477999
S546 O-Glycosylation GlyGen 30459171
S549 O-Glycosylation GlyGen 30459171
S549 Phosphorylation phospho.ELM   PhosphoSitePlus 18088087
S551 Phosphorylation PhosphoSitePlus
T555 Phosphorylation PhosphoSitePlus
T557 O-Glycosylation GlyGen 30459171
T557 Phosphorylation PhosphoSitePlus
S560 Phosphorylation UniProt 26091039
S561 Phosphorylation PhosphoSitePlus
S562 O-Glycosylation GlyGen   PhosphoSitePlus 23584533, 30459171
S572 Phosphorylation PhosphoSitePlus
S576 Phosphorylation phospho.ELM 1956339
S577 Phosphorylation phospho.ELM 1956339
S578 Phosphorylation phospho.ELM 1956339
S586 O-Glycosylation GlyGen   PhosphoSitePlus 23584533
S594 Phosphorylation PhosphoSitePlus
K599 Acetylation PhosphoSitePlus
S609 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 3477999, 26091039, 18088087, ...24275569
S609 Phosphorylation P68400 (CSNK2A1) PhosphoSitePlus 3477999
T616 O-Glycosylation GlyGen   PhosphoSitePlus 23584533
S618 Phosphorylation phospho.ELM   PhosphoSitePlus 1956339
K620 Acetylation PhosphoSitePlus
K625 Acetylation PhosphoSitePlus
S626 Phosphorylation PhosphoSitePlus
N684 N-Glycosylation GlyGen 24190977
N686 N-Glycosylation GlyGen   UniProt 16335952, 19159218, 24190977, ...23090970, 9689040, 29741879
Site PTM Type PTM Enzyme Score Source PMID
S22 Phosphorylation HPRD 12729597, 20058876, 19117447
Y277 Phosphorylation HPRD 18083107
S356 Phosphorylation HPRD 20058876
S364 Phosphorylation HPRD 19562805, 19824718, 18088087, ...6719396, 20058876
S365 Phosphorylation HPRD 19562805, 20058876
T412 Phosphorylation HPRD 18088087
S460 Phosphorylation HPRD 81086167
S524 Phosphorylation HPRD 18088087
S549 Phosphorylation HPRD 18088087
S576 Phosphorylation HPRD 92065884
S577 Phosphorylation HPRD 92065884
S578 Phosphorylation HPRD 92065884
S609 Phosphorylation HPRD 18088087
S618 Phosphorylation HPRD 92065884
Site PTM Type PTM Enzyme Score Source PMID
S22 Phosphorylation HPRD 12729597, 20058876, 19117447
Y277 Phosphorylation HPRD 18083107
S356 Phosphorylation HPRD 20058876
S364 Phosphorylation HPRD 19562805, 19824718, 18088087, ...6719396, 20058876
S365 Phosphorylation HPRD 19562805, 20058876
T412 Phosphorylation HPRD 18088087
S460 Phosphorylation HPRD 81086167
S524 Phosphorylation HPRD 18088087
S549 Phosphorylation HPRD 18088087
S609 Phosphorylation HPRD 18088087
K639 Acetylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S356 I356 Biomuta DOID:8618 / oral cavity cancer [ cosmic ] DOID:11934 / head and neck cancer [ icgc ]
S364 T364 Biomuta DOID:184 / bone cancer [ cosmic ]
S364 R364 Biomuta DOID:1324 / lung cancer [ cosmic ]
S365 F365 Biomuta DOID:1319 / brain cancer [ cosmic ]
S460 L460 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]