iPTMnet Report for P02042 (HBD)
Protein Information
| UniProt AC / UniProt ID | P02042 / HBD_HUMAN |
| Protein Name | Hemoglobin subunit delta |
| Gene Name | Name: HBD |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:P02042 |
| PRO Name | hemoglobin subunit delta (human) |
| Definition | A hemoglobin subunit delta that is encoded in the genome of human. |
| Short Label | hHBD |
| Category | organism-gene |
P02042 (HBD) as Substrate
| Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
|---|---|---|---|---|---|---|
| V2 | Acetylation | score2 | UniProt | 1787103 | ||
| T5 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K9 | Acetylation | score1 | PhosphoSitePlus | |||
| T10 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y36 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T39 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S45 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S50 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S51 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 24275569 | ||
| K60 | Acetylation | score1 | PhosphoSitePlus | |||
| K62 | Acetylation | score1 | PhosphoSitePlus | |||
| K66 | Acetylation | score1 | PhosphoSitePlus | |||
| K67 | Acetylation | score1 | PhosphoSitePlus | |||
| S73 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K83 | Acetylation | score1 | PhosphoSitePlus | |||
| T85 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S87 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S90 | Phosphorylation | score1 | PhosphoSitePlus | |||
| C94 | S-Nitrosylation | score0 | dbSNO | 25040305, 24105792 | ||
| K96 | Acetylation | score1 | PhosphoSitePlus | |||
| Y131 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K145 | Acetylation | score1 | PhosphoSitePlus | |||
| Y146 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus | 18083107 |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| T5 | A5 | Biomuta | DOID:5041 / esophageal cancer [ cosmic ] | |
| S45 | L45 | Biomuta | DOID:4159 / skin cancer [ cosmic ] | |
| S45 | F45 | Biomuta | DOID:4159 / skin cancer [ cosmic ] | |
| S51 | Y51 | Biomuta | DOID:1324 / lung cancer [ cosmic ] | |
| S51 | T51 | Biomuta | DOID:1324 / lung cancer [ cosmic ] | |
| K66 | R66 | Biomuta | DOID:10534 / stomach cancer [ cosmic ] DOID:1324 / lung cancer [ cosmic ] | |
| K66 | N66 | Biomuta | DOID:1324 / lung cancer [ cosmic ] | |
| K66 | E66 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
| K83 | R83 | Biomuta | DOID:1324 / lung cancer [ cosmic ] | |
| T85 | A85 | Biomuta | DOID:3571 / liver cancer [ cosmic ] | |
| S87 | Y87 | Biomuta | DOID:363 / uterine cancer [ cosmic ] | |
| S87 | P87 | Biomuta | DOID:10534 / stomach cancer [ cosmic ] | |
| K96 | E96 | Biomuta | DOID:2531 / hematologic cancer [ cosmic ] | |
| Y146 | C146 | Biomuta | DOID:363 / uterine cancer [ cosmic ] |
DAG View