iPTMnet Report for P02042 (HBD)
Protein Information
UniProt AC / UniProt ID | P02042 / HBD_HUMAN |
Protein Name | Hemoglobin subunit delta |
Gene Name | Name: HBD |
Organism | Homo sapiens (Human) |
PRO ID | PR:P02042 |
PRO Name | hemoglobin subunit delta (human) |
Definition | A hemoglobin subunit delta that is encoded in the genome of human. |
Short Label | hHBD |
Category | organism-gene |
P02042 (HBD) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
V2 | Acetylation | score2 | UniProt | 1787103 | ||
T5 | Phosphorylation | score1 | PhosphoSitePlus | |||
K9 | Acetylation | score1 | PhosphoSitePlus | |||
T10 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y36 | Phosphorylation | score1 | PhosphoSitePlus | |||
T39 | Phosphorylation | score1 | PhosphoSitePlus | |||
S45 | Phosphorylation | score1 | PhosphoSitePlus | |||
S50 | Phosphorylation | score1 | PhosphoSitePlus | |||
S51 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 24275569 | ||
K60 | Acetylation | score1 | PhosphoSitePlus | |||
K62 | Acetylation | score1 | PhosphoSitePlus | |||
K66 | Acetylation | score1 | PhosphoSitePlus | |||
K67 | Acetylation | score1 | PhosphoSitePlus | |||
S73 | Phosphorylation | score1 | PhosphoSitePlus | |||
K83 | Acetylation | score1 | PhosphoSitePlus | |||
T85 | Phosphorylation | score1 | PhosphoSitePlus | |||
S87 | Phosphorylation | score1 | PhosphoSitePlus | |||
S90 | Phosphorylation | score1 | PhosphoSitePlus | |||
C94 | S-Nitrosylation | score0 | dbSNO | 25040305, 24105792 | ||
K96 | Acetylation | score1 | PhosphoSitePlus | |||
Y131 | Phosphorylation | score1 | PhosphoSitePlus | |||
K145 | Acetylation | score1 | PhosphoSitePlus | |||
Y146 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus | 18083107 |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
T5 | A5 | Biomuta | DOID:5041 / esophageal cancer [ cosmic ] | |
S45 | L45 | Biomuta | DOID:4159 / skin cancer [ cosmic ] | |
S45 | F45 | Biomuta | DOID:4159 / skin cancer [ cosmic ] | |
S51 | Y51 | Biomuta | DOID:1324 / lung cancer [ cosmic ] | |
S51 | T51 | Biomuta | DOID:1324 / lung cancer [ cosmic ] | |
K66 | R66 | Biomuta | DOID:10534 / stomach cancer [ cosmic ] DOID:1324 / lung cancer [ cosmic ] | |
K66 | N66 | Biomuta | DOID:1324 / lung cancer [ cosmic ] | |
K66 | E66 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
K83 | R83 | Biomuta | DOID:1324 / lung cancer [ cosmic ] | |
T85 | A85 | Biomuta | DOID:3571 / liver cancer [ cosmic ] | |
S87 | Y87 | Biomuta | DOID:363 / uterine cancer [ cosmic ] | |
S87 | P87 | Biomuta | DOID:10534 / stomach cancer [ cosmic ] | |
K96 | E96 | Biomuta | DOID:2531 / hematologic cancer [ cosmic ] | |
Y146 | C146 | Biomuta | DOID:363 / uterine cancer [ cosmic ] |