iPTMnet Report for P01911 (HLA-DRB1)
Protein Information
| UniProt AC / UniProt ID | P01911 / DRB1_HUMAN |
| Protein Name | HLA class II histocompatibility antigen, DRB1 beta chain precursor |
| Gene Name | Name: HLA-DRB1 |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:P01911 |
| PRO Name | HLA class II histocompatibility antigen, DRB1 beta chain (human) |
| Definition | An MHC class II histocompatibility antigen beta chain DRB1 that is encoded in the genome of human. |
| Short Label | hHLA-DRB1 |
| Category | organism-gene |
DAG ViewP01911 (HLA-DRB1) as Substrate
 |
Site | PTM Type | PTM Enzyme | Score | Source | PMID |
|---|---|---|---|---|---|---|
| S10 | Phosphorylation | score1 | PhosphoSitePlus | |||
| C11 | Methylation | score1 | IEDB | 31844290 | ||
| T13 | Phosphorylation | score1 | PhosphoSitePlus | |||
| N48 | N-Glycosylation | score4 | GlyGen UniProt | 24190431, 19303388, 24190977 | ||
| K94 | Ubiquitination | score1 | PhosphoSitePlus | |||
| Y107 | Phosphorylation | score1 | PhosphoSitePlus | |||
| C108 | Methylation | score1 | IEDB | 31844290 | ||
| Y112 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T192 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K254 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S266 | Phosphorylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| C11 | S11 | Biomuta | DOID:1324 / lung cancer [ icgc ] DOID:2531 / hematologic cancer [ cosmic ] DOID:5041 / esophageal cancer [ cosmic ] DOID:9256 / colorectal cancer [ cosmic ] DOID:8618 / oral cavity cancer [ cosmic ] DOID:1319 / brain cancer [ cosmic ] DOID:11054 / urinary bladder cancer [ cosmic, icgc ] | |
| T13 | A13 | Biomuta | DOID:8618 / oral cavity cancer [ cosmic ] DOID:9256 / colorectal cancer [ cosmic ] DOID:1781 / thyroid gland cancer [ cosmic ] | |
| K94 | E94 | Biomuta | DOID:2531 / hematologic cancer [ cosmic ] | |
| Y107 | * | Biomuta | DOID:8618 / oral cavity cancer [ cosmic ] |
