iPTMnet Report for P01889 (HLA-B)


Protein Information

Cytoscape View


UniProt AC / UniProt ID P01889 / HLAB_HUMAN
Protein Name HLA class I histocompatibility antigen, B alpha chain precursor
Gene Name Name: HLA-B
Synonyms:HLAB;
Organism Homo sapiens (Human)

PRO ID PR:P01889
DAG View
PRO Name HLA class I histocompatibility antigen, B-7 alpha chain (human)
Definition An HLA class I histocompatibility antigen B alpha chain (human) that belongs to to allele group 7.
Short Label hHLA-B*7
Category organism-seqgroup

Interactive Sequence View

Select/align proteoforms across species


P01889 (HLA-B) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
Y51 Phosphorylation PhosphoSitePlus
R86 Methylation PhosphoSitePlus
K92 Ubiquitination PhosphoSitePlus
N110 N-Glycosylation UniProt 19159218
Y123 Phosphorylation PhosphoSitePlus
K145 Ubiquitination PhosphoSitePlus
K200 Ubiquitination PhosphoSitePlus
K202 Ubiquitination PhosphoSitePlus
T211 Phosphorylation PhosphoSitePlus
K267 Ubiquitination PhosphoSitePlus
S275 Phosphorylation PhosphoSitePlus
K292 Ubiquitination PhosphoSitePlus
K340 Ubiquitination PhosphoSitePlus
Y344 Phosphorylation P12931 (SRC) HPRD   phospho.ELM   PhosphoSitePlus 1956339, 6304688
S350 Phosphorylation phospho.ELM   PhosphoSitePlus 6430898
S352 Phosphorylation PhosphoSitePlus
S356 Phosphorylation PhosphoSitePlus
S359 Phosphorylation HPRD   PhosphoSitePlus 20166139, 6430898
T361 Phosphorylation HPRD   PhosphoSitePlus 20166139


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
Y51 C51 Biomuta DOID:3571 / liver cancer [ tcga ]
R86 G86 Biomuta DOID:11054 / urinary bladder cancer [ icgc ]
Y123 F123 Biomuta DOID:1324 / lung cancer [ icgc ]
Y123 C123 Biomuta DOID:1324 / lung cancer [ icgc ]
K202 T202 Biomuta DOID:3963 / thyroid carcinoma [ icgc ]
K292 E292 Biomuta DOID:4159 / skin cancer [ icgc ]
Y344 C344 Biomuta DOID:2531 / hematologic cancer [ tcga ]