Protein Information

Cytoscape View


UniProt AC / UniProt ID P01861 / IGHG4_HUMAN
Protein Name Immunoglobulin heavy constant gamma 4
Gene Name Name: IGHG4
Organism Homo sapiens (Human)

PRO ID PR:P01861
DAG View
PRO Name immunoglobulin heavy constant gamma 4 (human)
Definition An immunoglobulin heavy constant gamma 4 that is encoded in the genome of human.
Short Label hIGHG4
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P01861 (IGHG4) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
T18 Phosphorylation PhosphoSitePlus
S21 Phosphorylation PhosphoSitePlus
T22 Phosphorylation PhosphoSitePlus
T130 Phosphorylation PhosphoSitePlus
S134 Phosphorylation PhosphoSitePlus
N177 N-Glycosylation UniProt 19139490, 19159218
K202 Acetylation PhosphoSitePlus
S244 Phosphorylation PhosphoSitePlus
T246 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
N177 K177 Biomuta DOID:2531 / hematologic cancer [ tcga ]
K202 N202 Biomuta DOID:363 / uterine cancer [ tcga ]
K202 * Biomuta DOID:263 / kidney cancer [ cosmic, tcga ]