iPTMnet Report P01861 IGHG4

Protein Information

Cytoscape View

UniProt AC / UniProt ID	P01861 / IGHG4_HUMAN
Protein Name	Immunoglobulin heavy constant gamma 4
Gene Name	Name: IGHG4
Organism	Homo sapiens (Human)

PRO ID	PR:P01861 DAG View
PRO Name	immunoglobulin heavy constant gamma 4 (human)
Definition	An immunoglobulin heavy constant gamma 4 that is encoded in the genome of human.
Short Label	hIGHG4
Category	organism-gene

Interactive Sequence View

	Select/align proteoforms across species

P01861 (IGHG4) as Substrate

Expanded View

	Site	PTM Type	PTM Enzyme	Score	Source	PMID
	T18	Phosphorylation		score1	PhosphoSitePlus
	S21	Phosphorylation		score1	PhosphoSitePlus
	T22	Phosphorylation		score1	PhosphoSitePlus
	T130	Phosphorylation		score1	PhosphoSitePlus
	S134	Phosphorylation		score1	PhosphoSitePlus
	N177	N-Glycosylation		score4	GlyGen UniProt	11406581, 34725484, 20357243, ...19159218, 24190977, 24530628, 29391424, 19139490, 24841998, 2363690, 18514042, 29741879, 24766575, 29671580, 29992770, 30659065
	K202	Acetylation		score1	PhosphoSitePlus
	S244	Phosphorylation		score1	PhosphoSitePlus
	T246	Phosphorylation		score1	PhosphoSitePlus

	Site	PTM Type	PTM Enzyme	Score	Source	PMID
	N177	N-Glycosylation		score3	PRO	24766575, 24841998, 29671580, ...30659065

PTM sites affected in variants

Site	Variant	Source	PMID	Disease [Sample source]
N177	K177	Biomuta		DOID:2531 / hematologic cancer [ icgc ]