Protein Information

Cytoscape View


UniProt AC / UniProt ID P01833 / PIGR_HUMAN
Protein Name Polymeric immunoglobulin receptor precursor
Gene Name Name: PIGR
Organism Homo sapiens (Human)

PRO ID PR:P01833
DAG View
PRO Name polymeric immunoglobulin receptor (human)
Definition A polymeric immunoglobulin receptor that is encoded in the genome of human.
Short Label hPIGR
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P01833 (PIGR) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
C64 S-Nitrosylation dbSNO 25040305
N83 N-Glycosylation GlyGen   UniProt 6526384, 32125861, 23662732, ...15084671, 16740002, 18780401
N90 N-Glycosylation GlyGen   UniProt 16335952, 6526384, 32125861, ...23662732, 15084671, 16740002, 18780401
S124 Phosphorylation PhosphoSitePlus
S128 Phosphorylation PhosphoSitePlus
N135 N-Glycosylation GlyGen   UniProt 29741879, 6526384, 23662732, ...32125861, 18780401
T137 Phosphorylation PhosphoSitePlus
T147 Phosphorylation PhosphoSitePlus
T149 Phosphorylation PhosphoSitePlus
N186 N-Glycosylation GlyGen   UniProt 6526384, 32125861, 23662732, ...26791533, 16740002, 18780401, 29741879
C220 S-Nitrosylation dbSNO 25040305
S274 Phosphorylation HPRD   PhosphoSitePlus 20068231
S275 Phosphorylation PhosphoSitePlus
T313 Phosphorylation PhosphoSitePlus
Y323 Phosphorylation PhosphoSitePlus
S350 Phosphorylation PhosphoSitePlus
T351 Phosphorylation PhosphoSitePlus
Y373 Phosphorylation HPRD 20068231
C385 S-Nitrosylation dbSNO 25040305
C395 S-Nitrosylation dbSNO 25040305
N421 N-Glycosylation GlyGen   UniProt 16335952, 6526384, 30237853, ...19159218, 23662732, 32125861, 15084671, 16740002, 18780401, 29741879
N469 N-Glycosylation GlyGen   UniProt 16335952, 6526384, 30237853, ...19159218, 24190977, 23090970, 23662732, 26791533, 32125861, 15084671, 19139490, 16740002, 18780401, 29741879
N499 N-Glycosylation GlyGen   UniProt 6526384, 30237853, 32125861, ...24190977, 23090970, 23662732, 16740002, 18780401, 29741879, 29671580
C544 S-Nitrosylation dbSNO 25040305
T555 Phosphorylation PhosphoSitePlus
S570 Phosphorylation PhosphoSitePlus
T614 O-Glycosylation GlyGen 30237853
S624 O-Glycosylation GlyGen 30237853
S627 O-Glycosylation GlyGen 30237853
S630 O-Glycosylation GlyGen 30237853
S630 Phosphorylation PhosphoSitePlus
S636 Phosphorylation PhosphoSitePlus
S673 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   RLIMS-P 22025622, 10809756
S676 Phosphorylation PhosphoSitePlus
Y677 Phosphorylation RLIMS-P 22025622
T679 Phosphorylation PhosphoSitePlus
S682 Phosphorylation PhosphoSitePlus   RLIMS-P 22025622
S684 Phosphorylation PhosphoSitePlus
S689 Phosphorylation PhosphoSitePlus
S734 Phosphorylation RLIMS-P 22025622
S735 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   RLIMS-P 22025622, 10809756
Y743 Phosphorylation RLIMS-P 22025622


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
N83 K83 Biomuta DOID:3571 / liver cancer [ icgc ]
S128 N128 Biomuta DOID:1909 / melanoma [ tcga ]
T147 M147 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc, tcga ]
C220 F220 Biomuta DOID:263 / kidney cancer [ cosmic, icgc, tcga ]
C395 * Biomuta DOID:3571 / liver cancer [ icgc ]
S676 R676 Biomuta DOID:2531 / hematologic cancer [ icgc ]
T679 A679 Biomuta DOID:3070 / malignant glioma [ tcga ]
T679 K679 Biomuta DOID:3571 / liver cancer [ icgc ]
S684 L684 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc, tcga ]
S734 L734 Biomuta DOID:1612 / breast cancer [ cosmic, icgc, tcga ]