iPTMnet Report for P01833 (PIGR)


Protein Information

Cytoscape View


UniProt AC / UniProt ID P01833 / PIGR_HUMAN
Protein Name Polymeric immunoglobulin receptor precursor
Gene Name Name: PIGR
Organism Homo sapiens (Human)

PRO ID PR:P01833
DAG View
PRO Name polymeric immunoglobulin receptor (human)
Definition A polymeric immunoglobulin receptor that is encoded in the genome of human.
Short Label hPIGR
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P01833 (PIGR) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
C64 S-Nitrosylation dbSNO 25040305
N83 N-Glycosylation GlyGen   UniProt 6526384, 32125861, 23662732, ...15084671, 16740002, 18780401
N90 N-Glycosylation GlyGen   UniProt 16335952, 6526384, 32125861, ...23662732, 15084671, 16740002, 18780401
S124 Phosphorylation PhosphoSitePlus
S128 Phosphorylation PhosphoSitePlus
N135 N-Glycosylation GlyGen   UniProt 29741879, 6526384, 23662732, ...32125861, 18780401
T137 Phosphorylation PhosphoSitePlus
T147 Phosphorylation PhosphoSitePlus
T149 Phosphorylation PhosphoSitePlus
N186 N-Glycosylation GlyGen   UniProt 6526384, 32125861, 23662732, ...26791533, 16740002, 18780401, 20030399, 29741879
C220 S-Nitrosylation dbSNO 25040305
S274 Phosphorylation HPRD   PhosphoSitePlus 20068231
S275 Phosphorylation PhosphoSitePlus
T313 Phosphorylation PhosphoSitePlus
Y323 Phosphorylation PhosphoSitePlus
S350 Phosphorylation PhosphoSitePlus
T351 Phosphorylation PhosphoSitePlus
Y373 Phosphorylation HPRD 20068231
C385 S-Nitrosylation dbSNO 25040305
C395 S-Nitrosylation dbSNO 25040305
N421 N-Glycosylation GlyGen   UniProt 16335952, 6526384, 30237853, ...19159218, 23662732, 32125861, 15084671, 16740002, 18780401, 20030399, 29741879
N469 N-Glycosylation GlyGen   UniProt 16335952, 6526384, 30237853, ...19159218, 24190977, 23090970, 23662732, 26791533, 32125861, 15084671, 19139490, 16740002, 18780401, 29741879
N499 N-Glycosylation GlyGen   UniProt 6526384, 30237853, 32125861, ...24190977, 23090970, 23662732, 16740002, 18780401, 20030399, 29741879, 29671580
C544 S-Nitrosylation dbSNO 25040305
T555 Phosphorylation PhosphoSitePlus
S570 Phosphorylation PhosphoSitePlus
T614 O-Glycosylation GlyGen 30237853
S624 O-Glycosylation GlyGen 30237853
S627 O-Glycosylation GlyGen 30237853
S630 O-Glycosylation GlyGen 30237853
S630 Phosphorylation PhosphoSitePlus
S636 Phosphorylation PhosphoSitePlus
S673 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus 10809756
S676 Phosphorylation PhosphoSitePlus
T679 Phosphorylation PhosphoSitePlus
S682 Phosphorylation PhosphoSitePlus
S684 Phosphorylation PhosphoSitePlus
S689 Phosphorylation PhosphoSitePlus
S735 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus 10809756
Site PTM Type PTM Enzyme Score Source PMID
N186 N-Glycosylation PRO 26791533
N469 N-Glycosylation PRO 26791533
N499 N-Glycosylation PRO 29671580


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S128 N128 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
T147 M147 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc ]
C220 F220 Biomuta DOID:263 / kidney cancer [ cosmic, icgc ]
N469 K469 Biomuta DOID:4159 / skin cancer [ cosmic ]
T555 I555 Biomuta DOID:1324 / lung cancer [ cosmic ]
S627 F627 Biomuta DOID:4159 / skin cancer [ cosmic ]
T679 A679 Biomuta DOID:1319 / brain cancer [ icgc ]
S684 L684 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc ]