iPTMnet Report for P01732 (CD8A)
Protein Information
UniProt AC / UniProt ID | P01732 / CD8A_HUMAN |
Protein Name | T-cell surface glycoprotein CD8 alpha chain precursor |
Gene Name | Name: CD8A Synonyms:MAL; |
Organism | Homo sapiens (Human) |
PRO ID | PR:P01732 |
PRO Name | T-cell surface glycoprotein CD8 alpha chain (human) |
Definition | A T-cell surface glycoprotein CD8 alpha chain that is encoded in the genome of human. |
Short Label | hCD8A |
Category | organism-gene |
P01732 (CD8A) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
S158 | O-Glycosylation | score1 | GlyGen | 30459171 | ||
S224 | Phosphorylation | score1 | PhosphoSitePlus | |||
S229 | Phosphorylation | score1 | PhosphoSitePlus | |||
S231 | Phosphorylation | score1 | PhosphoSitePlus |
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
S158 | Phosphorylation | score1 | PhosphoSitePlus | |||
K190 | Ubiquitination | score1 | PhosphoSitePlus |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
S158 | Y158 | Biomuta | DOID:3571 / liver cancer [ cosmic ] | |
S224 | * | Biomuta | DOID:8618 / oral cavity cancer [ cosmic ] DOID:2531 / hematologic cancer [ cosmic ] | |
S229 | R229 | Biomuta | DOID:1324 / lung cancer [ cosmic ] | |
S231 | L231 | Biomuta | DOID:363 / uterine cancer [ icgc ] DOID:8618 / oral cavity cancer [ cosmic ] DOID:3571 / liver cancer [ cosmic ] DOID:11934 / head and neck cancer [ icgc ] |