iPTMnet Report for P01732 (CD8A)


Protein Information

Cytoscape View


UniProt AC / UniProt ID P01732 / CD8A_HUMAN
Protein Name T-cell surface glycoprotein CD8 alpha chain precursor
Gene Name Name: CD8A
Synonyms:MAL;
Organism Homo sapiens (Human)

PRO ID PR:P01732
DAG View
PRO Name T-cell surface glycoprotein CD8 alpha chain (human)
Definition A T-cell surface glycoprotein CD8 alpha chain that is encoded in the genome of human.
Short Label hCD8A
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P01732 (CD8A) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S158 O-Glycosylation GlyGen 30459171
S224 Phosphorylation PhosphoSitePlus
S229 Phosphorylation PhosphoSitePlus
S231 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S158 Phosphorylation PhosphoSitePlus
K190 Ubiquitination PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S158 Y158 Biomuta DOID:3571 / liver cancer [ cosmic ]
S224 * Biomuta DOID:8618 / oral cavity cancer [ cosmic ] DOID:2531 / hematologic cancer [ cosmic ]
S229 R229 Biomuta DOID:1324 / lung cancer [ cosmic ]
S231 L231 Biomuta DOID:363 / uterine cancer [ icgc ] DOID:8618 / oral cavity cancer [ cosmic ] DOID:3571 / liver cancer [ cosmic ] DOID:11934 / head and neck cancer [ icgc ]