iPTMnet Report for P01591 (JCHAIN)


Protein Information

Cytoscape View


UniProt AC / UniProt ID P01591 / IGJ_HUMAN
Protein Name Immunoglobulin J chain precursor
Gene Name Name: JCHAIN
Synonyms:IGCJ,IGJ;
Organism Homo sapiens (Human)

PRO ID PR:P01591
DAG View
PRO Name immunoglobulin J chain (human)
Definition An immunoglobulin J chain that is encoded in the genome of human.
Short Label hJCHAIN
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P01591 (JCHAIN) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K21 Ubiquitination PhosphoSitePlus
K34 Ubiquitination PhosphoSitePlus
K36 Ubiquitination PhosphoSitePlus
S48 Phosphorylation PhosphoSitePlus
N67 N-Glycosylation GlyGen 24190977
N68 N-Glycosylation GlyGen 24190977
N71 N-Glycosylation GlyGen 16335952, 108268, 29427759, ...19159218, 24190977, 23090970, 30237853, 25802287, 29391424, 32125861, 15084671, 19139490, 24841998, 16740002, 18780401, 20030399, 29741879, 24766575, 29671580, 26510530, 34725484
S73 Phosphorylation PhosphoSitePlus
T76 Phosphorylation PhosphoSitePlus
S77 Phosphorylation PhosphoSitePlus
S88 Phosphorylation PhosphoSitePlus
K92 Ubiquitination PhosphoSitePlus
K93 Ubiquitination PhosphoSitePlus
T97 O-Glycosylation GlyGen 26598643
T109 O-Glycosylation GlyGen 30459171
K130 Ubiquitination PhosphoSitePlus
C131 Methylation IEDB 31844290
K145 Ubiquitination PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
N71 N-Glycosylation PRO 108268, 24766575, 24841998, ...25802287, 29671580


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
N71 K71 Biomuta DOID:263 / kidney cancer [ cosmic ]
S77 L77 Biomuta DOID:4606 / bile duct cancer [ cosmic ] DOID:2531 / hematologic cancer [ cosmic, icgc ]
S88 F88 Biomuta DOID:10534 / stomach cancer [ cosmic ]
C131 * Biomuta DOID:10534 / stomach cancer [ cosmic ]