iPTMnet Report for P01583 (IL1A)
Protein Information
| UniProt AC / UniProt ID | P01583 / IL1A_HUMAN |
| Protein Name | Interleukin-1 alpha precursor |
| Gene Name | Name: IL1A Synonyms:IL1F1; |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:P01583 |
| PRO Name | interleukin-1 alpha (human) |
| Definition | An interleukin-1 alpha that is encoded in the genome of human. |
| Short Label | hIL1A |
| Category | organism-gene |
DAG ViewP01583 (IL1A) as Substrate
 |
Site | PTM Type | PTM Enzyme | Score | Source | PMID |
|---|---|---|---|---|---|---|
| S16 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T59 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S60 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T66 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K82 | Acetylation | score2 | UniProt | 26439902 | ||
| K82 | Myristoylation | score2 | UniProt | 8346241 | ||
| K83 | Myristoylation | score2 | UniProt | 8346241 | ||
| S87 | Phosphorylation | score3 | HPRD PhosphoSitePlus | 3126184 | ||
| S104 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T189 | Phosphorylation | score1 | PhosphoSitePlus |
Proteoforms
| PRO ID (Short Label) | Sites | PTM Enzyme | Source | PMID | |
|---|---|---|---|---|---|
| PR:000036598 (hIL1A/iso:1/Myr:1) | myK83 | PRO | 8346241 | ||
| PR:000036599 (hIL1A/iso:1/Myr:2) | myK82 | PRO | 8346241 |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| S16 | I16 | Biomuta | DOID:4159 / skin cancer [ cosmic, icgc ] | |
| S60 | T60 | Biomuta | [ cosmic ] | |
| S87 | T87 | Biomuta | DOID:1324 / lung cancer [ cosmic ] |
