iPTMnet Report for P01375 (TNF)


Protein Information

Cytoscape View


UniProt AC / UniProt ID P01375 / TNFA_HUMAN
Protein Name Tumor necrosis factor precursor
Gene Name Name: TNF
Synonyms:TNFA,TNFSF2;
Organism Homo sapiens (Human)

PRO ID PR:P01375
DAG View
PRO Name tumor necrosis factor (human)
Definition A tumor necrosis factor that is encoded in the genome of human.
Short Label hTNF
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P01375 (TNF) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S2 Phosphorylation HPRD   phospho.ELM 8597870
S2 Phosphorylation Q8N165 (PDIK1L) HPRD 8597870
K19 Myristoylation UniProt 1402651, 23552949
K20 Myristoylation UniProt 1402651, 23552949
S80 O-Glycosylation GlyGen   UniProt 8631363
S162 Phosphorylation PhosphoSitePlus
S171 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S2 Phosphorylation PRO 8597870, 10205166
K19 Myristoylation PRO 1402651
K20 Myristoylation PRO 1402651


Proteoforms

PRO ID (Short Label) Sites PTM Enzyme Source PMID
PR:000036507 (hTNF/iso:1/Myr:1) myK19,myK20 PRO 1402651
PR:000036508 (hTNF/iso:1/Phos:1) pS2 PRO 10205166, 8597870


Proteoform PPIs

Protein 1 Relation Protein 2 Source PMID
PR:000036504 (hTNF/iso:1/Clv:1) Interaction PR:P19438 (hTNFRSF1A) PRO 14512626
PR:000036504 (hTNF/iso:1/Clv:1) Interaction PR:000036504 (hTNF/iso:1/Clv:1) PRO 14512626