iPTMnet Report P01344 IGF2

Protein Information

Cytoscape View

UniProt AC / UniProt ID	P01344 / IGF2_HUMAN
Protein Name	Insulin-like growth factor II precursor
Gene Name	Name: IGF2 ORFNames:PP1446;
Organism	Homo sapiens (Human)

PRO ID	PR:P01344 DAG View
PRO Name	insulin-like growth factor II (human)
Definition	An insulin-like growth factor II that is encoded in the genome of human.
Short Label	hIGF2
Category	organism-gene

Interactive Sequence View

	Select/align proteoforms across species

P01344 (IGF2) as Substrate

P01344

Condensed View

	Site	PTM Type	PTM Enzyme	Score	Source	PMID
	S57	O-Glycosylation		score1	GlyGen	31492838
	S60	O-Glycosylation		score1	GlyGen	31492838
	Y83	Phosphorylation		score1	PhosphoSitePlus
	S95	O-Glycosylation		score1	GlyGen	30237853
	T96	O-Glycosylation		score2	GlyGen UniProt	30459171, 23234360, 22171320, ...30237853
	T99	O-Glycosylation		score4	GlyGen UniProt	1569071, 30459171, 23234360, ...22171320, 30237853
	Y116	Phosphorylation		score1	PhosphoSitePlus
	T163	O-Glycosylation		score2	GlyGen UniProt	19838169, 23234360, 22171320

PTM sites affected in variants

Site	Variant	Source	PMID	Disease [Sample source]
S95	L95	Biomuta		DOID:363 / uterine cancer [ cosmic, icgc ]
T163	S163	Biomuta		DOID:2531 / hematologic cancer [ cosmic, icgc ]