Protein Information

Cytoscape View


UniProt AC / UniProt ID P01275 / GLUC_HUMAN
Protein Name Glucagon precursor
Gene Name Name: GCG
Organism Homo sapiens (Human)

PRO ID PR:P01275
DAG View
PRO Name glucagon (human)
Definition A glucagon that is encoded in the genome of human.
Short Label hGCG
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P01275 (GCG) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
T26 Phosphorylation PhosphoSitePlus
S32 Phosphorylation PhosphoSitePlus
S34 Phosphorylation PhosphoSitePlus
S36 Phosphorylation PhosphoSitePlus
S42 Phosphorylation PhosphoSitePlus
S54 Phosphorylation PhosphoSitePlus
Y62 Phosphorylation PhosphoSitePlus
S68 Phosphorylation PhosphoSitePlus
S150 Phosphorylation PhosphoSitePlus
S152 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
T26 K26 Biomuta DOID:3571 / liver cancer [ icgc ]
Y62 * Biomuta DOID:1909 / melanoma [ cosmic ]
S68 F68 Biomuta DOID:1909 / melanoma [ cosmic ]
S150 F150 Biomuta DOID:1909 / melanoma [ tcga ]
S150 Y150 Biomuta DOID:363 / uterine cancer [ tcga ] DOID:9256 / colorectal cancer [ tcga ] DOID:1909 / melanoma [ cosmic ]
S152 F152 Biomuta DOID:1909 / melanoma [ icgc, tcga ]