iPTMnet Report for P01266 (TG)
Protein Information
| UniProt AC / UniProt ID | P01266 / THYG_HUMAN |
| Protein Name | Thyroglobulin precursor |
| Gene Name | Name: TG |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:P01266 |
| PRO Name | thyroglobulin (human) |
| Definition | A thyroglobulin that is encoded in the genome of human. |
| Short Label | hTG |
| Category | organism-gene |
DAG ViewP01266 (TG) as Substrate
 |
Site | PTM Type | PTM Enzyme | Score | Source | PMID |
|---|---|---|---|---|---|---|
| N76 | N-Glycosylation | score4 | GlyGen UniProt | 8615697, 32025030 | ||
| N110 | N-Glycosylation | score3 | GlyGen UniProt | 32025030 | ||
| N198 | N-Glycosylation | score4 | GlyGen UniProt | 8615697, 32025030 | ||
| Y234 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S240 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y376 | Phosphorylation | score1 | PhosphoSitePlus | |||
| N484 | N-Glycosylation | score4 | GlyGen UniProt | 8615697, 32025030 | ||
| N529 | N-Glycosylation | score3 | GlyGen UniProt | 8615697 | ||
| N748 | N-Glycosylation | score3 | GlyGen UniProt | 8615697 | ||
| N816 | N-Glycosylation | score3 | GlyGen UniProt | 8615697 | ||
| T939 | Phosphorylation | score1 | PhosphoSitePlus | |||
| N947 | N-Glycosylation | score4 | GlyGen UniProt | 8615697, 32025030 | ||
| Y1005 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y1165 | Phosphorylation | score1 | PhosphoSitePlus | |||
| N1220 | N-Glycosylation | score4 | GlyGen UniProt | 8615697, 32025030 | ||
| N1348 | N-Glycosylation | score3 | GlyGen UniProt | 8615697 | ||
| N1349 | N-Glycosylation | score4 | GlyGen UniProt | 8615697, 32025030 | ||
| N1365 | N-Glycosylation | score4 | GlyGen UniProt | 29741879, 8615697, 32025030 | ||
| T1421 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y1529 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S1577 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S1591 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S1652 | Phosphorylation | score1 | PhosphoSitePlus | |||
| N1716 | N-Glycosylation | score4 | GlyGen UniProt | 8615697, 32025030 | ||
| N1774 | N-Glycosylation | score4 | GlyGen UniProt | 8615697, 32025030 | ||
| N1869 | N-Glycosylation | score3 | GlyGen UniProt | 32025030 | ||
| N2013 | N-Glycosylation | score4 | GlyGen UniProt | 8615697, 32025030 | ||
| N2122 | N-Glycosylation | score3 | GlyGen UniProt | 32025030 | ||
| Y2184 | Phosphorylation | score1 | PhosphoSitePlus | |||
| N2250 | N-Glycosylation | score4 | GlyGen UniProt | 8615697, 32025030 | ||
| N2295 | N-Glycosylation | score4 | GlyGen UniProt | 8615697, 32025030 | ||
| T2467 | Phosphorylation | score1 | PhosphoSitePlus | |||
| N2582 | N-Glycosylation | score4 | GlyGen UniProt | 8615697, 32025030 | ||
| Y2658 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y2670 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S2728 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S2737 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S2740 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S2749 | O-Glycosylation | score3 | GlyGen UniProt | 16679516 |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| N198 | S198 | Biomuta | DOID:10534 / stomach cancer [ cosmic, icgc ] | |
| T939 | M939 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
| Y1165 | C1165 | Biomuta | DOID:1324 / lung cancer [ cosmic ] | |
| N1365 | D1365 | Biomuta | DOID:10534 / stomach cancer [ cosmic, icgc ] | |
| T1421 | I1421 | Biomuta | DOID:363 / uterine cancer [ cosmic, icgc ] | |
| S1591 | Y1591 | Biomuta | DOID:1324 / lung cancer [ cosmic, icgc ] | |
| S1591 | F1591 | Biomuta | DOID:4159 / skin cancer [ cosmic, icgc ] | |
| N2295 | S2295 | Biomuta | DOID:363 / uterine cancer [ cosmic, icgc ] |
