iPTMnet Report for P01258 (CALCA)


Protein Information

Cytoscape View


UniProt AC / UniProt ID P01258 / CALC_HUMAN
Protein Name Calcitonin precursor
Gene Name Name: CALCA
Synonyms:CALC1;
Organism Homo sapiens (Human)

PRO ID PR:P01258
DAG View
PRO Name calcitonin isoforms 1/2 (human)
Definition A calcitonin (human), isoforms 1 and 2.
Short Label hCALCA/iso:[1/h2]
Category organism-seqgroup

Interactive Sequence View

Select/align proteoforms across species


P01258 (CALCA) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S35 Phosphorylation PhosphoSitePlus
T41 Phosphorylation PhosphoSitePlus
S89 Phosphorylation PhosphoSitePlus
T97 Phosphorylation PhosphoSitePlus
T105 O-Glycosylation GlyGen   PhosphoSitePlus 23584533
T105 Phosphorylation PhosphoSitePlus
T109 O-Glycosylation GlyGen   PhosphoSitePlus 23584533


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S35 G35 Biomuta [ cosmic ]
S35 T35 Biomuta DOID:1612 / breast cancer [ cosmic, icgc ]
T41 K41 Biomuta DOID:1324 / lung cancer [ cosmic ]
T41 R41 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
T105 A105 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
T105 M105 Biomuta DOID:10534 / stomach cancer [ cosmic ]