Protein Information

Cytoscape View


UniProt AC / UniProt ID P01042 / KNG1_HUMAN
Protein Name Kininogen-1 precursor
Gene Name Name: KNG1
Synonyms:BDK,KNG;
Organism Homo sapiens (Human)

PRO ID PR:P01042
DAG View
PRO Name kininogen-1 (human)
Definition A kininogen-1 that is encoded in the genome of human.
Short Label hKNG1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P01042 (KNG1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
N48 N-Glycosylation GlyGen   UniProt 16335952, 23090970, 29391424, ...19139490, 25265424, 29741879, 29671580
T110 Phosphorylation PhosphoSitePlus
K113 Acetylation PhosphoSitePlus
S120 O-Glycosylation GlyGen 30459171
T137 O-Glycosylation GlyGen 30459171, 26598643
S150 O-Glycosylation GlyGen 30459171, 26598643
T151 O-Glycosylation GlyGen 30459171, 26598643
N169 N-Glycosylation GlyGen   UniProt 16335952, 24530628, 19159218, ...3484703, 14760718, 29391424, 23090970, 25265424, 29741879, 29671580
T171 Phosphorylation PhosphoSitePlus
S174 Phosphorylation PhosphoSitePlus
S175 Phosphorylation PhosphoSitePlus
N205 N-Glycosylation GlyGen   UniProt 16335952, 24530628, 30237853, ...19159218, 23090970, 29391424, 3484703, 19139490, 25265424, 29741879, 29671580, 24417605
T273 O-Glycosylation GlyGen 30459171
S275 Phosphorylation PhosphoSitePlus
N294 N-Glycosylation GlyGen   UniProt 16335952, 24530628, 30237853, ...19159218, 23090970, 14760718, 29391424, 32125861, 19139490, 19838169, 24279413, 25265424, 29741879, 12754519, 29671580
T326 Phosphorylation PhosphoSitePlus
T327 Phosphorylation PhosphoSitePlus
S329 Phosphorylation PhosphoSitePlus
S332 Phosphorylation PhosphoSitePlus   UniProt 19824718, 26091039, 24275569
T337 Phosphorylation PhosphoSitePlus
T342 Phosphorylation PhosphoSitePlus
S386 Phosphorylation PhosphoSitePlus
S390 Phosphorylation PhosphoSitePlus
S391 Phosphorylation PhosphoSitePlus
T400 O-Glycosylation GlyGen 30459171
T401 O-Glycosylation GlyGen 30459171
T407 O-Glycosylation GlyGen 30459171
S408 O-Glycosylation GlyGen 30459171
S531 O-Glycosylation GlyGen 30459171
T532 O-Glycosylation GlyGen 30459171
T533 O-Glycosylation GlyGen   UniProt 4054110, 30459171
T542 O-Glycosylation GlyGen 30459171, 24417605
T546 O-Glycosylation GlyGen   UniProt 4054110, 30459171
S550 O-Glycosylation GlyGen 30459171
T571 O-Glycosylation GlyGen 26598643
S577 O-Glycosylation GlyGen 26598643
S599 O-Glycosylation GlyGen 30459171
S604 O-Glycosylation GlyGen 30459171, 26598643
N626 N-Glycosylation GlyGen 29391424
Site PTM Type PTM Enzyme Score Source PMID
T326 Phosphorylation HPRD 19824718
T327 Phosphorylation HPRD 19824718
S329 Phosphorylation HPRD 19824718, 20166139
S332 Phosphorylation HPRD 19824718, 20166139, 20187088
Site PTM Type PTM Enzyme Score Source PMID
T326 Phosphorylation HPRD 19824718
T327 Phosphorylation HPRD 19824718
S329 Phosphorylation HPRD 19824718, 20166139
S332 Phosphorylation HPRD 19824718, 20166139, 20187088
T401 Phosphorylation PhosphoSitePlus
S402 Phosphorylation PhosphoSitePlus
S406 Phosphorylation PhosphoSitePlus
S422 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
N48 K48 Biomuta DOID:1324 / lung cancer [ cosmic ]
T110 I110 Biomuta DOID:1324 / lung cancer [ cosmic, icgc, tcga ]
S175 F175 Biomuta DOID:1909 / melanoma [ tcga ]
N205 T205 Biomuta DOID:263 / kidney cancer [ cosmic, icgc, tcga ]
N205 I205 Biomuta DOID:1324 / lung cancer [ tcga ]
S275 N275 Biomuta DOID:363 / uterine cancer [ cosmic, tcga ] DOID:10534 / stomach cancer [ cosmic, icgc, tcga ]
T326 A326 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc, tcga ]
T326 P326 Biomuta DOID:3571 / liver cancer [ icgc ] DOID:0070003 / blastoma [ cosmic ]
S386 L386 Biomuta DOID:1909 / melanoma [ icgc, tcga ]
T532 I532 Biomuta DOID:363 / uterine cancer [ cosmic, icgc, tcga ] DOID:9256 / colorectal cancer [ tcga ]
S577 L577 Biomuta DOID:1612 / breast cancer [ tcga ] DOID:11934 / head and neck cancer [ tcga ]
S599 L599 Biomuta DOID:1909 / melanoma [ tcga ]
S604 L604 Biomuta DOID:1612 / breast cancer [ tcga ] DOID:1909 / melanoma [ tcga ] DOID:11934 / head and neck cancer [ tcga ]
N626 S626 Biomuta DOID:1324 / lung cancer [ tcga ]