Protein Information

Cytoscape View

UniProt AC / UniProt ID P01036 / CYTS_HUMAN
Protein Name Cystatin-S precursor
Gene Name Name: CST4
Organism Homo sapiens (Human)

PRO ID PR:P01036
DAG View
PRO Name cystatin-S (human)
Definition A cystatin-S that is encoded in the genome of human.
Short Label hCST4
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species

P01036 (CST4) as Substrate

Site PTM Type PTM Enzyme Score Source PMID
T7 Phosphorylation PhosphoSitePlus
S21 Phosphorylation HPRD   PhosphoSitePlus   UniProt 1778989, 20189825
S23 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 1778989, 1747107, 1898055, ...20189825, 1741693
Y35 Phosphorylation PhosphoSitePlus
Y63 Phosphorylation PhosphoSitePlus
S119 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus 1898055, 91378515
S132 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus 1898055, 91378515
S136 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus 1898055, 91378515

PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
Y35 C35 Biomuta DOID:1324 / lung cancer [ tcga ]
Y63 * Biomuta DOID:1909 / melanoma [ cosmic ] DOID:3571 / liver cancer [ icgc ]
S119 F119 Biomuta DOID:1790 / malignant mesothelioma [ tcga ]
S136 T136 Biomuta DOID:10534 / stomach cancer [ cosmic ]