iPTMnet Report for P01036 (CST4)
Protein Information
UniProt AC / UniProt ID | P01036 / CYTS_HUMAN |
Protein Name | Cystatin-S precursor |
Gene Name | Name: CST4 |
Organism | Homo sapiens (Human) |
PRO ID | PR:P01036 |
PRO Name | cystatin-S (human) |
Definition | A cystatin-S that is encoded in the genome of human. |
Short Label | hCST4 |
Category | organism-gene |
P01036 (CST4) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
T7 | Phosphorylation | score1 | PhosphoSitePlus | |||
S21 | Phosphorylation | score4 | HPRD PhosphoSitePlus UniProt | 1778989, 20189825 | ||
S23 | Phosphorylation | score4 | HPRD phospho.ELM PhosphoSitePlus UniProt | 1778989, 1747107, 1898055, ... | ||
Y35 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y63 | Phosphorylation | score1 | PhosphoSitePlus | |||
S119 | Phosphorylation | score4 | HPRD phospho.ELM PhosphoSitePlus | 1898055, 91378515 | ||
S132 | Phosphorylation | score4 | HPRD phospho.ELM PhosphoSitePlus | 1898055, 91378515 | ||
S136 | Phosphorylation | score4 | HPRD phospho.ELM PhosphoSitePlus | 1898055, 91378515 |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
S23 | F23 | Biomuta | DOID:4159 / skin cancer [ cosmic ] | |
Y35 | C35 | Biomuta | DOID:1324 / lung cancer [ cosmic, icgc ] | |
Y63 | * | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
S119 | F119 | Biomuta | DOID:4159 / skin cancer [ cosmic ] | |
S136 | T136 | Biomuta | DOID:10534 / stomach cancer [ cosmic ] |