iPTMnet Report for P01033 (TIMP1)


Protein Information

Cytoscape View


UniProt AC / UniProt ID P01033 / TIMP1_HUMAN
Protein Name Metalloproteinase inhibitor 1 precursor
Gene Name Name: TIMP1
Synonyms:CLGI,TIMP;
Organism Homo sapiens (Human)

PRO ID PR:P01033
DAG View
PRO Name metalloproteinase inhibitor 1 (human)
Definition A metalloproteinase inhibitor 1 that is encoded in the genome of human.
Short Label hTIMP1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P01033 (TIMP1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K45 Ubiquitination PhosphoSitePlus
N53 N-Glycosylation GlyGen 16335952, 30237853, 8053566, ...24190977, 23090970, 26791533, 32125861, 16263699, 19139490, 16740002, 29741879
K70 Ubiquitination PhosphoSitePlus
N101 N-Glycosylation GlyGen 32125861, 8053566, 24190977, ...23090970, 16740002, 29741879
C168 Methylation IEDB 31844290
S178 Phosphorylation UniProt 26091039
K180 Ubiquitination PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
N53 N-Glycosylation PRO 26791533, 8053566
N101 N-Glycosylation PRO 8053566


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
N101 S101 Biomuta DOID:363 / uterine cancer [ icgc ]
K180 N180 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]