iPTMnet Report P01019 AGT

Protein Information

Cytoscape View

UniProt AC / UniProt ID	P01019 / ANGT_HUMAN
Protein Name	Angiotensinogen precursor
Gene Name	Name: AGT Synonyms:SERPINA8;
Organism	Homo sapiens (Human)

PRO ID	PR:P01019 DAG View
PRO Name	angiotensinogen (human)
Definition	An angiotensinogen that is encoded in the genome of human.
Short Label	hAGT
Category	organism-gene

Interactive Sequence View

	Select/align proteoforms across species

P01019 (AGT) as Substrate

Expanded View

	Site	PTM Type	PTM Enzyme	Score	Source	PMID
	S8	O-Glycosylation		score1	GlyGen	30620550
	S16	O-Glycosylation		score1	GlyGen	30620550
	N47	N-Glycosylation		score4	GlyGen UniProt	16335952, 34725484, 32125861, ...19159218, 24190977, 23090970, 3934016, 29741879, 29671580, 24417605
	K100	Ubiquitination		score1	PhosphoSitePlus
	N170	N-Glycosylation		score4	GlyGen UniProt	23090970, 24190977, 3934016, ...24417605
	K287	Acetylation		score1	PhosphoSitePlus
	N304	N-Glycosylation		score4	GlyGen UniProt	24417605, 3934016
	N328	N-Glycosylation		score3	GlyGen UniProt	3934016
	T440	O-Glycosylation		score1	GlyGen	30459171

	Site	PTM Type	PTM Enzyme	Score	Source	PMID
	N47	N-Glycosylation		score1	PRO	29671580

PTM sites affected in variants

Site	Variant	Source	PMID	Disease [Sample source]
N170	K170	Biomuta		DOID:2394 / ovarian cancer [ cosmic, icgc ]
K287	N287	Biomuta		DOID:1319 / brain cancer [ icgc ]