Protein Information

Cytoscape View


UniProt AC / UniProt ID P00973 / OAS1_HUMAN
Protein Name 2'-5'-oligoadenylate synthase 1
Gene Name Name: OAS1
Synonyms:OIAS;
Organism Homo sapiens (Human)

PRO ID PR:P00973
DAG View
PRO Name 2'-5'-oligoadenylate synthase 1 (human)
Definition A 2'-5'-oligoadenylate synthase 1 that is encoded in the genome of human.
Short Label hOAS1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P00973 (OAS1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K10 Ubiquitination PhosphoSitePlus
K42 Acetylation PhosphoSitePlus
S49 Phosphorylation PhosphoSitePlus
S50 Phosphorylation PhosphoSitePlus
S116 Phosphorylation PhosphoSitePlus
K182 Ubiquitination PhosphoSitePlus
K199 Ubiquitination PhosphoSitePlus
K213 Ubiquitination PhosphoSitePlus
K220 Ubiquitination PhosphoSitePlus
Y271 Phosphorylation PhosphoSitePlus
K279 Ubiquitination PhosphoSitePlus
K314 Ubiquitination PhosphoSitePlus
Y362 Phosphorylation PhosphoSitePlus
Y367 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S338 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S49 T49 Biomuta DOID:1324 / lung cancer [ tcga ]
S50 C50 Biomuta DOID:1324 / lung cancer [ cosmic ]
Y271 C271 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc, tcga ]