iPTMnet Report for P00915 (CA1)


Protein Information

Cytoscape View


UniProt AC / UniProt ID P00915 / CAH1_HUMAN
Protein Name Carbonic anhydrase 1
Gene Name Name: CA1
Organism Homo sapiens (Human)

PRO ID PR:P00915
DAG View
PRO Name carbonic anhydrase 1 (human)
Definition A vertebrate-type carbonic anhydrase 1 that is encoded in the genome of human.
Short Label hCA1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P00915 (CA1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
A2 Acetylation UniProt 4217196, 4207120
S30 Phosphorylation PhosphoSitePlus
S49 Phosphorylation PhosphoSitePlus
S51 Phosphorylation PhosphoSitePlus
T56 Phosphorylation PhosphoSitePlus
S78 Phosphorylation PhosphoSitePlus
S86 Phosphorylation PhosphoSitePlus
S88 Phosphorylation PhosphoSitePlus
Y89 Phosphorylation PhosphoSitePlus
S130 O-Glycosylation GlyGen   PhosphoSitePlus 24126823, 18984734
S131 Phosphorylation PhosphoSitePlus
S137 Phosphorylation PhosphoSitePlus
K157 Acetylation PhosphoSitePlus
S218 O-Glycosylation GlyGen   PhosphoSitePlus 24126823, 18984734


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
A2 V2 Biomuta DOID:363 / uterine cancer [ icgc ]
T56 A56 Biomuta DOID:1324 / lung cancer [ cosmic ]
T56 R56 Biomuta DOID:1324 / lung cancer [ cosmic ]
S88 R88 Biomuta DOID:9256 / colorectal cancer [ cosmic ]