iPTMnet Report for P00813 (ADA)


Protein Information

Cytoscape View


UniProt AC / UniProt ID P00813 / ADA_HUMAN
Protein Name Adenosine deaminase
Gene Name Name: ADA
Synonyms:ADA1;
Organism Homo sapiens (Human)

PRO ID PR:P00813
DAG View
PRO Name adenosine deaminase (human)
Definition An adenosine deaminase that is encoded in the genome of human.
Short Label hADA
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P00813 (ADA) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
T4 Phosphorylation PhosphoSitePlus
K9 Acetylation PhosphoSitePlus
K9 Ubiquitination PhosphoSitePlus
K23 Ubiquitination PhosphoSitePlus
T26 Phosphorylation PhosphoSitePlus
Y29 Phosphorylation PhosphoSitePlus
Y30 Phosphorylation PhosphoSitePlus
K54 Acetylation PhosphoSitePlus   UniProt 19608861
K54 Ubiquitination PhosphoSitePlus
Y67 Phosphorylation PhosphoSitePlus
Y84 Phosphorylation PhosphoSitePlus
K90 Ubiquitination PhosphoSitePlus
K92 Ubiquitination PhosphoSitePlus
K111 Ubiquitination PhosphoSitePlus
K147 Ubiquitination PhosphoSitePlus
S162 Phosphorylation PhosphoSitePlus
K164 Acetylation PhosphoSitePlus
K164 Ubiquitination PhosphoSitePlus
K170 Acetylation PhosphoSitePlus
K170 Ubiquitination PhosphoSitePlus
K171 Ubiquitination PhosphoSitePlus
K206 Ubiquitination PhosphoSitePlus
K225 Ubiquitination PhosphoSitePlus
K232 Acetylation PhosphoSitePlus   UniProt 19608861
K232 Ubiquitination PhosphoSitePlus
Y240 Phosphorylation PhosphoSitePlus
Y249 Phosphorylation PhosphoSitePlus
K273 Ubiquitination PhosphoSitePlus
K284 Ubiquitination PhosphoSitePlus
Y290 Phosphorylation PhosphoSitePlus
S291 Phosphorylation PhosphoSitePlus
K301 Ubiquitination PhosphoSitePlus
Y308 Phosphorylation PhosphoSitePlus
K312 Acetylation PhosphoSitePlus
K312 Ubiquitination PhosphoSitePlus
K323 Acetylation PhosphoSitePlus
K323 Ubiquitination PhosphoSitePlus
K331 Ubiquitination PhosphoSitePlus
K340 Ubiquitination PhosphoSitePlus
Y348 Phosphorylation PhosphoSitePlus
Y351 Phosphorylation PhosphoSitePlus
S358 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
Y29 * Biomuta DOID:363 / uterine cancer [ cosmic ]
Y67 C67 Biomuta DOID:1324 / lung cancer [ cosmic ]
K147 N147 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ]
K232 M232 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc ]
S291 L291 Biomuta DOID:9253 / gastrointestinal stromal tumor [ cosmic ]
K301 T301 Biomuta DOID:5041 / esophageal cancer [ cosmic ]
K312 R312 Biomuta DOID:1612 / breast cancer [ cosmic, icgc ]
K331 E331 Biomuta DOID:363 / uterine cancer [ icgc ]
K340 N340 Biomuta DOID:11054 / urinary bladder cancer [ cosmic, icgc ]
Y351 C351 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc ]