iPTMnet Report for P00533 (EGFR)


Protein Information

Cytoscape View


UniProt AC / UniProt ID P00533 / EGFR_HUMAN
Protein Name Epidermal growth factor receptor precursor
Gene Name Name: EGFR
Synonyms:ERBB,ERBB1,HER1;
Organism Homo sapiens (Human)

PRO ID PR:P00533
DAG View
PRO Name epidermal growth factor receptor (human)
Definition An epidermal growth factor receptor that is encoded in the genome of human.
Short Label hEGFR
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P00533 (EGFR) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K37 Sumoylation PhosphoSitePlus
N56 N-Glycosylation GlyGen 12297050, 20837704, 12297049, ...12731890, 16083266, 10988252, 29391424, 10731668
N73 N-Glycosylation GlyGen   UniProt 20837704
S77 Phosphorylation PhosphoSitePlus
Y88 Phosphorylation RLIMS-P 28245430
Y112 Phosphorylation PhosphoSitePlus
Y113 Phosphorylation PhosphoSitePlus
Y117 Phosphorylation PhosphoSitePlus
N128 N-Glycosylation GlyGen   UniProt 10731668, 8962717, 12731890, ...16083266, 10988252
K133 Acetylation PhosphoSitePlus
S151 Phosphorylation PhosphoSitePlus
N175 N-Glycosylation GlyGen   UniProt 8962717, 12297050, 29391424, ...12731890, 16083266, 20837704, 10988252, 10731668
C190 S-Nitrosylation dbSNO 19056486, 22178444
N196 N-Glycosylation GlyGen   UniProt 12297050, 12297049, 12731890, ...16083266, 20837704, 29741879
K212 Ubiquitination PhosphoSitePlus
R222 Methylation PhosphoSitePlus
R224 Methylation PhosphoSitePlus
S229 Phosphorylation neXtProt   PhosphoSitePlus   RLIMS-P   UniProt 21487020
S229 Phosphorylation P31749 (AKT1) PhosphoSitePlus 21487020
K253 Acetylation PhosphoSitePlus
N271 N-Glycosylation GlyGen 29391424
K284 Acetylation PhosphoSitePlus
T290 Phosphorylation PhosphoSitePlus
C291 S-Nitrosylation dbSNO 20140087, 22178444
K293 Ubiquitination PhosphoSitePlus
C311 S-Nitrosylation dbSNO 20140087, 22178444
C329 S-Nitrosylation dbSNO 19056486, 22178444
K346 Acetylation PhosphoSitePlus
N352 N-Glycosylation GlyGen   UniProt 12297050, 19159218, 24190977, ...23090970, 12297049, 12731890, 16083266, 20837704, 10988252, 29741879, 10731668, 12620237
T354 Phosphorylation PhosphoSitePlus
N361 N-Glycosylation GlyGen   UniProt 12297050, 24190977, 23090970, ...29391424, 12731890, 16083266, 20837704, 10988252, 29741879, 10731668, 12620237
S364 O-Glycosylation GlyGen 33214551, 26108188, 31492838, ...30059200, 34019948, 30962710, 35289036, 28510447, 33465208, 29237092
S380 O-Glycosylation GlyGen 33214551, 26108188, 31492838, ...30059200, 34019948, 30962710, 35289036, 28510447, 33465208, 29237092
K396 Ubiquitination PhosphoSitePlus
N413 N-Glycosylation GlyGen   UniProt 8962717, 19159218, 12731890, ...16083266, 10988252, 29741879, 10731668
T430 O-Glycosylation GlyGen 33214551, 26108188, 31492838, ...30059200, 34019948, 30962710, 35289036, 28510447, 33465208, 29237092
T430 Phosphorylation PhosphoSitePlus
S437 O-Glycosylation GlyGen 33465208
S442 O-Glycosylation GlyGen 33465208
N444 N-Glycosylation GlyGen   UniProt 8962717, 12297050, 20837704, ...12731890, 16083266, 10988252, 10731668, 12620237
S457 Phosphorylation PhosphoSitePlus
N468 N-Glycosylation GlyGen 29391424
C470 S-Nitrosylation dbSNO 20140087, 22178444
T474 O-Glycosylation GlyGen 33214551, 26108188, 31492838, ...30059200, 34019948, 30962710, 35289036, 28510447, 33465208, 29237092
K479 Ubiquitination PhosphoSitePlus
K487 Ubiquitination PhosphoSitePlus
K489 Ubiquitination PhosphoSitePlus
S511 Phosphorylation PhosphoSitePlus
N528 N-Glycosylation GlyGen   UniProt 8962717, 25922362, 12731890, ...16083266, 20837704, 10988252, 10731668, 12620237
K538 Ubiquitination PhosphoSitePlus
N568 N-Glycosylation GlyGen   UniProt 19159218, 12731890, 16083266, ...10988252, 10731668, 12620237
Y585 Phosphorylation PhosphoSitePlus
N603 N-Glycosylation GlyGen   UniProt 24190977, 23090970, 29391424, ...12731890, 16083266, 10988252, 29741879, 10731668, 12620237
N623 N-Glycosylation GlyGen   UniProt 23090970, 24190977, 12731890
S645 Phosphorylation PhosphoSitePlus
T648 Phosphorylation PhosphoSitePlus
L654 Phosphorylation IntAct 20692258
T678 Phosphorylation neXtProt   phospho.ELM   PhosphoSitePlus   RLIMS-P   Signor   UniProt 34155348, 6090944, 15302935, ...3379075, 21749319, 1860884, 10816576, 12359306, 10523301
T678 Phosphorylation P17252 (PRKCA) PhosphoSitePlus   Signor 6090944, 3379075, 10816576, ...12359306
T678 Phosphorylation Q15139 (PRKD1) neXtProt 10523301
T678 Phosphorylation Q16512 (PKN1) neXtProt   PhosphoSitePlus   Signor 21749319
T678 Phosphorylation Q6P5Z2 (PKN3) PhosphoSitePlus 21749319
T693 Phosphorylation neXtProt   phospho.ELM   PhosphoSitePlus   RLIMS-P   Signor   UniProt 18669648, 16785992, 17192257, ...1939237, 2543683, 22703031, 18691976, 23186163, 34086370, 23723255, 24275569, 34295309, 1651323, 1651322, 18220336, 10523301, 17081983, 15302935, 16083266, 2115882, 3138233, 20068231
T693 Phosphorylation P27361 (MAPK3) neXtProt   phospho.ELM   PhosphoSitePlus   Signor 1939237, 1651322
T693 Phosphorylation P28482 (MAPK1) neXtProt   phospho.ELM   PhosphoSitePlus 1939237, 1651322
T693 Phosphorylation Q15139 (PRKD1) neXtProt 10523301
T693 Phosphorylation Q16539 (MAPK14) neXtProt   PhosphoSitePlus 16785992
S695 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18691976, 15302935, 1956339, ...18669648, 3138233
K708 Ubiquitination PhosphoSitePlus
K713 Ubiquitination PhosphoSitePlus
K714 Ubiquitination PhosphoSitePlus
K716 Ubiquitination PhosphoSitePlus   UniProt 16543144, 33996800
S720 Phosphorylation PhosphoSitePlus
T725 Phosphorylation PhosphoSitePlus
Y727 Phosphorylation IntAct   PhosphoSitePlus 15657067, 16729043
Y727 Phosphorylation P12931 (SRC) PhosphoSitePlus 15657067
K728 Ubiquitination PhosphoSitePlus
K737 Ubiquitination PhosphoSitePlus   UniProt 16543144, 33996800
K739 Ubiquitination PhosphoSitePlus
K745 Methylation PhosphoSitePlus
K745 Ubiquitination PhosphoSitePlus
S752 Phosphorylation PhosphoSitePlus
K754 Ubiquitination PhosphoSitePlus   UniProt 16543144, 33996800
K757 Ubiquitination PhosphoSitePlus   UniProt 33996800
Y764 Phosphorylation PhosphoSitePlus 15657067
Y764 Phosphorylation P12931 (SRC) PhosphoSitePlus 15657067
S768 Phosphorylation neXtProt   phospho.ELM   PhosphoSitePlus   RLIMS-P   Signor 15302935, 10347170, 29695735
S768 Phosphorylation Q9UQM7 (CAMK2A) neXtProt   Signor 10347170
T790 Phosphorylation RLIMS-P 25375092, 30925736, 27279914, ...32512509, 26629323
Y801 Phosphorylation PhosphoSitePlus
N816 N-Glycosylation GlyGen 29391424
K823 Ubiquitination PhosphoSitePlus
Y827 Phosphorylation PhosphoSitePlus
V845 Phosphorylation IntAct 23866081
K846 Ubiquitination PhosphoSitePlus
K852 Ubiquitination PhosphoSitePlus
K860 Ubiquitination PhosphoSitePlus
K867 Ubiquitination PhosphoSitePlus   UniProt 16543144, 33996800
Y869 Phosphorylation IntAct   neXtProt   phospho.ELM   PhosphoSitePlus   RLIMS-P   Signor   UniProt 17877814, 25427151, 23774213, ...10075741, 11983694, 19305428, 22231447, 33328764, 19935697, 31492560, 17646646, 18083107, 17653080, 10653583, 16273093, 14512423, 16943190
Y869 Phosphorylation P00533 (EGFR) neXtProt   PhosphoSitePlus   Signor 10653583, 17646646, 19935697
Y869 Phosphorylation P12931 (SRC) neXtProt   phospho.ELM   PhosphoSitePlus   Signor 10075741, 19305428, 16943190, ...14512423, 11983694
Y869 Phosphorylation Q13882 (PTK6) neXtProt 22231447
K875 Ubiquitination PhosphoSitePlus
Y891 Phosphorylation IntAct   PhosphoSitePlus 16729043
T892 Phosphorylation PhosphoSitePlus 26143491
T892 Phosphorylation Q13131 (PRKAA1) PhosphoSitePlus 26143491
K913 Ubiquitination PhosphoSitePlus
Y915 Phosphorylation IntAct   neXtProt   phospho.ELM   PhosphoSitePlus 11983694, 16273093, 7797556
Y915 Phosphorylation P12931 (SRC) neXtProt   phospho.ELM 11983694, 7797556
K929 Ubiquitination PhosphoSitePlus   UniProt 16543144
T940 Phosphorylation PhosphoSitePlus
Y944 Phosphorylation IntAct   neXtProt   phospho.ELM   PhosphoSitePlus 11983694, 7797556
Y944 Phosphorylation P12931 (SRC) neXtProt   phospho.ELM 11983694, 7797556
K960 Ubiquitination PhosphoSitePlus   UniProt 33996800
K970 Ubiquitination PhosphoSitePlus   UniProt 16543144
Y978 Phosphorylation IntAct   phospho.ELM   PhosphoSitePlus 16729043, 12070153, 16097034
S991 Phosphorylation phospho.ELM   PhosphoSitePlus   RLIMS-P   UniProt 17081983, 15901825, 18220336, ...29802988, 16083266, 18669648, 24275569, 20068231, 19531499
T993 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
S995 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648
Y998 Phosphorylation IntAct   neXtProt   phospho.ELM   PhosphoSitePlus   RLIMS-P   UniProt 19563760, 17081983, 31725811, ...15951569, 18669648, 22559222, 17646646, 16729043, 16273093, 19531499
Y998 Phosphorylation P00533 (EGFR) neXtProt   UniProt 18669648, 19563760, 17646646
Y1016 Phosphorylation IntAct   neXtProt   phospho.ELM   PRO   PhosphoSitePlus   RLIMS-P   Signor   UniProt 19563760, 23774213, 1688559, ...7685104, 15302935, 10653583, 7680558, 8845374, 24935154, 7797556, 1314835, 8621392, 32245944, 17575160, 16729043, 7693694, 16273093, 16943190
Y1016 Phosphorylation P00519 (ABL1) PhosphoSitePlus 16943190
Y1016 Phosphorylation P00533 (EGFR) neXtProt   PhosphoSitePlus   Signor   UniProt 17575160, 1688559, 19563760, ...1314835, 10653583
Y1016 Phosphorylation P12931 (SRC) neXtProt   phospho.ELM   PhosphoSitePlus   Signor 17575160, 7797556, 8845374
S1025 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
S1026 Phosphorylation neXtProt   phospho.ELM   PhosphoSitePlus   Signor   UniProt 15302935, 18669648, 16083266, ...24275569, 8360196
S1026 Phosphorylation P06493 (CDK1) neXtProt   phospho.ELM   PhosphoSitePlus   Signor 8360196
S1028 Phosphorylation phospho.ELM 18669648, 15302935
S1030 Phosphorylation PhosphoSitePlus
T1032 Phosphorylation PhosphoSitePlus
S1037 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
S1039 Phosphorylation neXtProt   phospho.ELM   PhosphoSitePlus   RLIMS-P   UniProt 18669648, 24797263, 17081983, ...19531499
S1039 Phosphorylation Q15759 (MAPK11) PhosphoSitePlus 19531499
S1039 Phosphorylation Q16539 (MAPK14) PhosphoSitePlus 19531499
T1041 Phosphorylation neXtProt   phospho.ELM   PhosphoSitePlus   RLIMS-P   UniProt 18669648, 19531499
T1041 Phosphorylation Q15759 (MAPK11) PhosphoSitePlus 19531499
T1041 Phosphorylation Q16539 (MAPK14) PhosphoSitePlus 19531499
S1042 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 17081983
S1045 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648, 17081983
T1046 Phosphorylation PhosphoSitePlus
S1057 Phosphorylation PhosphoSitePlus
K1061 Acetylation PhosphoSitePlus
K1061 Ubiquitination PhosphoSitePlus
S1064 Phosphorylation phospho.ELM   PhosphoSitePlus   Signor   UniProt 18691976, 23186163, 17081983, ...18669648, 10347170, 20068231
S1064 Phosphorylation Q9UQM7 (CAMK2A) Signor 10347170
Y1069 Phosphorylation IntAct   neXtProt   phospho.ELM   PRO   PhosphoSitePlus   RLIMS-P   Signor   UniProt 19563760, 23774213, 19531499, ...15302935, 18669648, 22888118, 10635327, 16729043, 31460159, 17081983
Y1069 Phosphorylation P00533 (EGFR) neXtProt   Signor 19563760, 10635327
S1070 Phosphorylation neXtProt   phospho.ELM   PhosphoSitePlus   RLIMS-P   Signor   UniProt 7505275, 1309762, 28873083, ...23254288, 15302935, 1956339, 20877636, 10347170, 3138233, 7805884
S1070 Phosphorylation Q9UQM7 (CAMK2A) neXtProt   Signor 10347170, 1309762
S1071 Phosphorylation neXtProt   phospho.ELM   PhosphoSitePlus   RLIMS-P   Signor   UniProt 7505275, 1309762, 15302935, ...1956339, 20877636, 10347170, 3138233, 7805884
S1071 Phosphorylation Q13555 (CAMK2G) Signor 1309762
S1071 Phosphorylation Q9UQM7 (CAMK2A) neXtProt   Signor 10347170, 1309762
T1074 Phosphorylation PhosphoSitePlus
T1078 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
S1081 Phosphorylation phospho.ELM   PhosphoSitePlus   Signor   UniProt 18691976, 18669648, 10347170, ...15302935
S1081 Phosphorylation Q9UQM7 (CAMK2A) Signor 10347170
T1085 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
Y1092 Phosphorylation IntAct   neXtProt   phospho.ELM   PRO   PhosphoSitePlus   RLIMS-P   Signor   UniProt 3263271, 16943190, 28724430, ...14966128, 17646646, 27153536, 10229072, 17877814, 7527043, 11896612, 8940013, 15737014, 15329413, 16729043, 26370283, 12873986, 9363897, 31537844, 9153411, 23825523, 7993895, 8845374, 2543678, 7518560, 17726540, 9733788, 23774213, 17081983, 15302935, 1314835, 18083107, 10653583, 19531499
Y1092 Phosphorylation O60674 (JAK2) neXtProt 9363897
Y1092 Phosphorylation P00519 (ABL1) neXtProt   PhosphoSitePlus 16943190
Y1092 Phosphorylation P00533 (EGFR) neXtProt   phospho.ELM   PhosphoSitePlus   Signor   UniProt 3263271, 1314835, 2543678, ...8845374, 10653583, 17646646, 9733788, 12873986
S1096 Phosphorylation PhosphoSitePlus
K1099 Ubiquitination PhosphoSitePlus
S1104 Phosphorylation phospho.ELM   PhosphoSitePlus 17081983
Y1110 Phosphorylation IntAct   neXtProt   phospho.ELM   PRO   PhosphoSitePlus   RLIMS-P   Signor   UniProt 25168820, 17646646, 7527043, ...26921391, 12873986, 15302935, 8845374, 26274523, 7797556, 14966128, 2543678, 1314835, 10653583, 7518560, 16729043, 19935697, 2803273, 16273093
Y1110 Phosphorylation P00533 (EGFR) neXtProt   phospho.ELM   PhosphoSitePlus   Signor   UniProt 12873986, 1314835, 19935697, ...2543678, 8845374, 10653583, 17646646, 2803273
Y1110 Phosphorylation P12931 (SRC) neXtProt   Signor 7797556, 8845374
S1120 Phosphorylation PhosphoSitePlus   Signor 10347170
S1120 Phosphorylation Q9UQM7 (CAMK2A) Signor 10347170
Y1125 Phosphorylation IntAct   neXtProt   phospho.ELM   PhosphoSitePlus   Signor 10075741, 11983694, 8845374, ...16729043, 16273093
Y1125 Phosphorylation P12931 (SRC) neXtProt   phospho.ELM   PhosphoSitePlus   Signor 10075741, 8845374, 11983694
S1130 Phosphorylation PhosphoSitePlus
T1131 Phosphorylation PhosphoSitePlus
Y1138 Phosphorylation IntAct   neXtProt   PhosphoSitePlus 16729043, 17646646, 16273093
Y1138 Phosphorylation P00533 (EGFR) neXtProt 17646646
T1141 Phosphorylation PhosphoSitePlus
T1145 Phosphorylation PhosphoSitePlus
T1150 Phosphorylation PhosphoSitePlus
S1153 Phosphorylation PhosphoSitePlus
K1160 Ubiquitination PhosphoSitePlus
S1162 Phosphorylation PhosphoSitePlus
S1166 Phosphorylation neXtProt   phospho.ELM   PhosphoSitePlus   RLIMS-P   Signor   UniProt 22703031, 18691976, 29802988, ...15302935, 18669648, 10347170, 24275569
S1166 Phosphorylation Q9UQM7 (CAMK2A) neXtProt   Signor 10347170
Y1172 Phosphorylation IEDB   IntAct   neXtProt   phospho.ELM   PRO   PhosphoSitePlus   RLIMS-P   Signor   UniProt 18083107, 35494241, 3263271, ...17081983, 9733788, 15302935, 8845374, 16273093, 31492560, 22559222, 2543678, 1314835, 10653583, 27153536, 17646646, 16729043, 19935697, 27281782, 12454019, 16943190
Y1172 Phosphorylation P00519 (ABL1) Signor 16943190
Y1172 Phosphorylation P00533 (EGFR) neXtProt   phospho.ELM   PhosphoSitePlus   Signor   UniProt 3263271, 17081983, 1314835, ...19935697, 2543678, 8845374, 10653583, 17646646, 9733788
Y1172 Phosphorylation P12931 (SRC) Signor 8845374
K1179 Acetylation PhosphoSitePlus
K1179 Ubiquitination PhosphoSitePlus
K1182 Acetylation PhosphoSitePlus
K1182 Ubiquitination PhosphoSitePlus
K1188 Acetylation PhosphoSitePlus
K1188 Methylation PhosphoSitePlus
K1188 Ubiquitination PhosphoSitePlus
S1190 Phosphorylation phospho.ELM   PhosphoSitePlus 15302935
T1191 Phosphorylation PhosphoSitePlus
A1192 Phosphorylation IntAct 16273093
Y1197 Phosphorylation IntAct   neXtProt   phospho.ELM   PRO   PhosphoSitePlus   RLIMS-P   Signor   UniProt 3263271, 16943190, 30615629, ...17646646, 27153536, 22703031, 18691976, 9544989, 7693694, 16729043, 26370283, 19836242, 7542744, 8845374, 19935697, 31492560, 2543678, 7518560, 9733788, 23774213, 19563760, 29556515, 17081983, 15302935, 1314835, 18083107, 10653583, 20068231, 8034616
Y1197 Phosphorylation P00519 (ABL1) neXtProt   PhosphoSitePlus   Signor 16943190
Y1197 Phosphorylation P00533 (EGFR) neXtProt   phospho.ELM   PhosphoSitePlus   Signor   UniProt 3263271, 17081983, 1314835, ...19935697, 2543678, 8845374, 10653583, 17646646, 9733788
R1199 Methylation UniProt 21258366
Site PTM Type PTM Enzyme Score Source PMID
N56 N-Glycosylation PRO 10731668, 10988252
N128 N-Glycosylation PRO 10731668, 10988252
N175 N-Glycosylation PRO 10731668, 10988252
T290 Phosphorylation HPRD 18452278
N352 N-Glycosylation PRO 10731668, 10988252
N361 N-Glycosylation PRO 10731668, 10988252
N413 N-Glycosylation PRO 10731668, 10988252
N444 N-Glycosylation PRO 10731668, 10988252
N528 N-Glycosylation PRO 10731668, 10988252
N568 N-Glycosylation PRO 10731668, 10988252
N603 N-Glycosylation PRO 10731668, 10988252
T678 Phosphorylation HPRD 2987962, 2984676
T678 Phosphorylation Q05655 (PRKCD) HPRD 2987962, 2984676
T693 Phosphorylation HPRD 19413330, 18691976, 16799092, ...20058876, 15302935, 18669648, 18491316, 2543683, 18767875, 20068231
S695 Phosphorylation HPRD 18691976, 18669648, 18491316, ...92065884, 20068231
S720 Phosphorylation HPRD 20068231
T725 Phosphorylation HPRD 18691976, 20068231
Y727 Phosphorylation HPRD 16729043, 20068231
S768 Phosphorylation HPRD   PRO 10347170
S768 Phosphorylation Q9UQM7 (CAMK2A) HPRD 10347170
Y869 Phosphorylation HPRD   PRO 11983694, 16729043, 18789131
Y869 Phosphorylation P12931 (SRC) HPRD 11983694, 16729043
Y891 Phosphorylation HPRD 16729043
Y915 Phosphorylation HPRD 11983694, 16729043
Y915 Phosphorylation P12931 (SRC) HPRD 11983694, 16729043
Y944 Phosphorylation HPRD 11983694, 16729043
Y944 Phosphorylation P12931 (SRC) HPRD 11983694, 16729043
Y978 Phosphorylation HPRD 16729043
S991 Phosphorylation HPRD 18691976, 17389395, 19651622, ...18669648, 16799092, 20068231
T993 Phosphorylation HPRD 19651622, 18669648, 20068231
S995 Phosphorylation HPRD 19651622, 18669648, 17081983, ...20068231
Y998 Phosphorylation HPRD 17016520, 15951569, 16729043, ...17389395, 18669648
Y998 Phosphorylation P12931 (SRC) HPRD 17016520, 15951569, 16729043, ...17389395, 18669648
Y1016 Phosphorylation HPRD 16729043, 16799092, 8845374
Y1016 Phosphorylation P00533 (EGFR) HPRD 16799092, 8845374
S1025 Phosphorylation HPRD 18691976, 18669648, 20068231
S1026 Phosphorylation HPRD 18691976, 18669648, 16799092
S1028 Phosphorylation HPRD 18669648
S1036 Phosphorylation HPRD 18691976, 17081983
S1037 Phosphorylation HPRD 18691976, 18669648, 17081983
S1039 Phosphorylation HPRD 18691976, 18669648, 17081983
T1041 Phosphorylation HPRD 18669648, 17081983
S1042 Phosphorylation HPRD 18691976, 18669648, 17081983
S1045 Phosphorylation HPRD 18767875, 18669648, 17081983
S1064 Phosphorylation HPRD 18691976, 18669648, 10347170, ...20068231
S1064 Phosphorylation Q9UQM7 (CAMK2A) HPRD 18691976, 18669648, 10347170, ...20068231
Y1069 Phosphorylation HPRD 17016520, 18691976, 17389395, ...9363897, 18669648, 16799092, 10635327
Y1069 Phosphorylation O60674 (JAK2) HPRD 17016520, 18691976, 17389395, ...9363897, 18669648, 16799092, 10635327
Y1069 Phosphorylation P00533 (EGFR) HPRD 17016520, 18691976, 17389395, ...9363897, 18669648, 16799092, 10635327
Y1069 Phosphorylation P04626 (ERBB2) HPRD 17016520, 18691976, 17389395, ...9363897, 18669648, 16799092, 10635327
S1070 Phosphorylation HPRD   PRO 16799092, 10347170, 1309762
S1070 Phosphorylation Q13555 (CAMK2G) HPRD 10347170, 16799092, 1309762
S1070 Phosphorylation Q9UQM7 (CAMK2A) HPRD 10347170, 1309762
S1071 Phosphorylation HPRD   PRO 10347170, 1309762
S1071 Phosphorylation Q13555 (CAMK2G) HPRD 10347170, 1309762
S1071 Phosphorylation Q9UQM7 (CAMK2A) HPRD 10347170, 1309762
T1078 Phosphorylation HPRD 18669648
S1081 Phosphorylation HPRD   PRO 18691976, 16799092, 10347170, ...18669648, 20068231
S1081 Phosphorylation Q9UQM7 (CAMK2A) HPRD 18691976, 18669648, 16799092, ...20068231, 10347170
T1085 Phosphorylation HPRD 18669648
Y1092 Phosphorylation HPRD 17016520, 11983694, 16799092, ...8845374
Y1092 Phosphorylation P00533 (EGFR) HPRD 17016520, 11983694, 16799092, ...8845374
Y1092 Phosphorylation P12931 (SRC) HPRD 17016520, 11983694, 16799092, ...8845374
Y1110 Phosphorylation HPRD 17016520, 16729043, 16799092, ...8845374, 18707149
Y1110 Phosphorylation P00533 (EGFR) HPRD 17016520, 16729043, 16799092, ...8845374, 18707149
S1120 Phosphorylation HPRD 10347170
S1120 Phosphorylation Q9UQM7 (CAMK2A) HPRD 10347170
Y1125 Phosphorylation HPRD 10075741, 16729043, 8845374, ...11983694
Y1125 Phosphorylation P12931 (SRC) HPRD 10075741, 16729043, 8845374, ...11983694
Y1138 Phosphorylation HPRD 16729043, 16799092
S1166 Phosphorylation HPRD   PRO 18691976, 17389395, 16799092, ...18669648, 10347170, 20166139, 20068231
S1166 Phosphorylation Q9UQM7 (CAMK2A) HPRD 18691976, 16799092, 10347170, ...18669648, 17389395, 20166139, 20068231
Y1172 Phosphorylation HPRD 17016520, 17389395, 8845374, ...19651622, 16799092, 16729043
Y1172 Phosphorylation P00533 (EGFR) HPRD 17016520, 17389395, 8845374, ...19651622, 16799092, 16729043
Y1197 Phosphorylation HPRD 17016520, 18691976, 16799092, ...17426253, 8845374, 17389395, 16729043, 20068231
Y1197 Phosphorylation P00533 (EGFR) HPRD 17016520, 18691976, 16799092, ...17426253, 8845374, 17389395, 16729043, 20068231
Site PTM Type PTM Enzyme Score Source PMID
T290 Phosphorylation HPRD 18452278
Site PTM Type PTM Enzyme Score Source PMID
T290 Phosphorylation HPRD 18452278
Site PTM Type PTM Enzyme Score Source PMID
T290 Phosphorylation HPRD 18452278


P00533 (EGFR) as PTM Enzyme



Substrate Site Score Source PMID
O14828-1 (SCAMP3) Y41 HPRD 9658162, 15144186
O14939-1 (PLD2) Y179 HPRD   Signor 9837959
O14939 (PLD2) Y296 neXtProt   PhosphoSitePlus 20176813
O14964 (HGS) Y329 HPRD   phospho.ELM   Signor 17016520, 12953068
O14964 (HGS) Y334 neXtProt   Signor 12953068
O15126-1 (SCAMP1) Y37 HPRD 9658162
O15455 (TLR3) Y858 PhosphoSitePlus 22810896
O15492 (RGS16) Y168 HPRD   neXtProt   phospho.ELM   PhosphoSitePlus   Signor 12588871, 11602604
O15492 (RGS16) Y177 HPRD   phospho.ELM   Signor 11602604
O60716 (CTNND1) Y228 HPRD   neXtProt   Signor 17016520, 17389395, 14996911, ...20068231
O75886-1 (STAM2) Y192 HPRD 19901323, 17389395, 10993906, ...11687594
O95477 (ABCA1) S2054 PhosphoSitePlus   Signor 12196520, 26494466
P00533 (EGFR) Y869 neXtProt   PhosphoSitePlus   Signor 10653583, 17646646, 19935697
P00533 (EGFR) Y998 neXtProt   UniProt 18669648, 19563760, 17646646
P00533-1 (EGFR) Y1016 HPRD   neXtProt   PhosphoSitePlus   Signor   UniProt 16799092, 1688559, 1314835, ...19563760, 8845374, 10653583, 17575160
P00533-1 (EGFR) Y1069 HPRD   neXtProt   Signor 17016520, 18691976, 17389395, ...19563760, 9363897, 18669648, 16799092, 10635327
P00533 (EGFR) Y1092 HPRD   neXtProt   phospho.ELM   PhosphoSitePlus   Signor   UniProt 17016520, 11983694, 3263271, ...1314835, 16799092, 2543678, 8845374, 10653583, 17646646, 9733788, 12873986
P00533 (EGFR) Y1110 HPRD   neXtProt   phospho.ELM   PhosphoSitePlus   Signor   UniProt 17016520, 16799092, 12873986, ...18707149, 1314835, 19935697, 2543678, 8845374, 10653583, 17646646, 16729043, 2803273
P00533 (EGFR) Y1138 neXtProt 17646646
P00533-1 (EGFR) Y1172 HPRD   neXtProt   phospho.ELM   PhosphoSitePlus   Signor   UniProt 17016520, 17389395, 17081983, ...8845374, 19935697, 19651622, 16799092, 2543678, 1314835, 10653583, 17646646, 16729043, 3263271, 9733788
P00533-1 (EGFR) Y1197 HPRD   neXtProt   phospho.ELM   PhosphoSitePlus   Signor   UniProt 17016520, 18691976, 16799092, ...17081983, 17426253, 8845374, 19935697, 17389395, 2543678, 1314835, 10653583, 17646646, 16729043, 3263271, 9733788, 20068231
P04083 (ANXA1) Y21 neXtProt   phospho.ELM   PhosphoSitePlus   Signor 24103589, 2457390
P04626-5 (ERBB2) Y1218 HPRD 11500516, 17426253, 17389395
P04626-1 (ERBB2) Y1248 HPRD   Signor 1706616, 17389395, 17426253, ...12354693
P07948 (LYN) Y32 PhosphoSitePlus 23764002
P09211 (GSTP1) Y4 neXtProt   PhosphoSitePlus   Signor 19254954
P09211 (GSTP1) Y8 neXtProt   PhosphoSitePlus   Signor 19254954
P09211 (GSTP1) Y199 neXtProt   PhosphoSitePlus   Signor 19254954
P0DP23 (CALM1) Y100 HPRD   Signor 17016520, 19901323, 18578522, ...17389395, 17287340, 18669648, 3415247, 18707149, 7925415, 12153558, 20068231, 16497976
P0DP24 (CALM2) Y100 Signor 3415247
P0DP25 (CALM3) Y100 Signor 3415247
P11171-4 (EPB41) Y418 HPRD   neXtProt   PhosphoSitePlus 1647028
P11171-3 (EPB41) Y437 HPRD 1647028
P11171 (EPB41) Y660 phospho.ELM   Signor 1647028
P12004 (PCNA) Y211 neXtProt   PhosphoSitePlus   Signor 22692198, 17115032, 25825764
P14618 (PKM) Y148 PhosphoSitePlus 26759242
P15311 (EZR) Y146 HPRD   neXtProt   phospho.ELM   PhosphoSitePlus   Signor 1382070, 15647376, 12560083
P15311 (EZR) Y354 HPRD   neXtProt   phospho.ELM   PhosphoSitePlus   Signor 1382070, 15647376
P15941-7 (MUC1) Y229 HPRD 11152665, 11483589
P15941-11 (MUC1) Y238 HPRD 11152665, 11483589
P15941-8 (MUC1) Y247 HPRD 11483589
P15941 (MUC1) Y1229 phospho.ELM   Signor 11483589
P18031 (PTPN1) Y66 HPRD   neXtProt   phospho.ELM   PhosphoSitePlus   Signor 11106648, 11506178, 9355745
P19174 (PLCG1) Y472 HPRD   neXtProt   Signor 19901323, 1689310, 12601080
P19174 (PLCG1) Y771 HPRD   neXtProt   phospho.ELM   PhosphoSitePlus   Signor 17016520, 17389395, 7682059, ...15144186, 8657103, 16038803, 1689310, 20068231, 16497976
P19174 (PLCG1) Y783 HPRD   neXtProt   phospho.ELM   PhosphoSitePlus   Signor 17016520, 20068231, 17389395, ...9176240, 7682059, 8657103, 16038803, 1689310, 8885868, 16497976
P19174 (PLCG1) Y1253 neXtProt   phospho.ELM   Signor 1689310
P20936-2 (RASA1) Y283 HPRD 1850098
P20936-1 (RASA1) Y460 HPRD   neXtProt   phospho.ELM   Signor 1850098
P21860 (ERBB3) Y1276 Signor 7929151
P21860 (ERBB3) Y1289 Signor 7929151
P22681 (CBL) Y371 neXtProt 10635327
P22681 (CBL) Y700 HPRD 11994282, 17389395, 11239464, ...15556646, 16497976
P22681 (CBL) Y731 HPRD 11994282, 10092522, 9890970, ...11239464, 10799548
P22681 (CBL) Y774 HPRD 11994282, 11239464, 15556646
P24844 (MYL9) Y143 phospho.ELM 8578591
P24844 (MYL9) Y156 phospho.ELM 8578591
P25098 (GRK2) Y13 neXtProt 18463167
P25098 (GRK2) Y86 neXtProt 18463167
P25098 (GRK2) Y92 neXtProt 18463167
P29353-3 (SHC1) Y194 PhosphoSitePlus 9388490
P29353-3 (SHC1) Y195 PhosphoSitePlus 9388490
P29353-2 (SHC1) Y239 neXtProt 9388490
P29353-2 (SHC1) Y240 neXtProt 9388490
P29353-3 (SHC1) Y272 PhosphoSitePlus 9388490
P29353-2 (SHC1) Y317 neXtProt 9388490
P30530 (AXL) Y779 RLIMS-P+ 27775700
P35222 (CTNNB1) Y142 PhosphoSitePlus 22558232
P35222 (CTNNB1) Y654 neXtProt   PhosphoSitePlus 14517306, 9233779
P37231-2 (PPARG) Y74 PhosphoSitePlus 26718225
P42224 (STAT1) Y701 HPRD   RLIMS-P+ 10918587, 7657660, 15322115, ...7543024, 11839738, 12817007, 7690989, 11294897, 12637327
P42566-1 (EPS15) Y849 HPRD   neXtProt   Signor 17016520, 10953014, 17389395, ...24269888
P46108-1 (CRK) Y221 HPRD   neXtProt   Signor 11956190, 17016520, 9642287, ...8875975, 9480911, 12198159, 20068231
P48050 (KCNJ4) Y234 PhosphoSitePlus 21486282
P51692 (STAT5B) Y699 HPRD   Signor 17016520, 11751923
P51692 (STAT5B) Y725 HPRD   phospho.ELM   Signor 11751923
P51692 (STAT5B) Y740 HPRD   phospho.ELM   Signor 11751923
P51692 (STAT5B) Y743 HPRD   phospho.ELM   Signor 11751923
P52735-3 (VAV2) Y142 HPRD   neXtProt   phospho.ELM   PhosphoSitePlus   Signor 17016520, 17389395, 10618391, ...12454019
P52735 (VAV2) Y159 HPRD   neXtProt   phospho.ELM   PhosphoSitePlus   Signor 11516622, 10618391, 12454019
P52735 (VAV2) Y172 HPRD   neXtProt   phospho.ELM   PhosphoSitePlus   Signor 10618391, 12454019
P61925 (PKIA) Y8 HPRD   neXtProt   phospho.ELM   Signor 2434500, 1956339
P62993-2 (GRB2) Y168 HPRD 11726515
P62993 (GRB2) Y209 phospho.ELM   Signor 11726515
P67775 (PPP2CA) Y307 neXtProt   PhosphoSitePlus 1325671
Q05397 (PTK2) Y5 neXtProt   PhosphoSitePlus   Signor 20802513
Q05397 (PTK2) Y194 neXtProt   PhosphoSitePlus   Signor 20802513
Q05655 (PRKCD) Y313 neXtProt 17956904
Q05655 (PRKCD) Y334 neXtProt 17956904
Q13315 (ATM) Y370 PhosphoSitePlus 25601159
Q13480 (GAB1) Y285 HPRD   neXtProt   phospho.ELM   PhosphoSitePlus   Signor 10734310, 9890893
Q13480-1 (GAB1) Y307 HPRD   phospho.ELM 10734310, 16497976
Q13480 (GAB1) Y373 HPRD   neXtProt   phospho.ELM   PhosphoSitePlus   Signor 10978177, 16497976, 17389395, ...9890893
Q13480-2 (GAB1) Y406 HPRD   neXtProt   phospho.ELM   PhosphoSitePlus   Signor 17016520, 19901323, 17389395, ...9890893, 10734310, 16497976
Q13480-2 (GAB1) Y447 HPRD   neXtProt   phospho.ELM   PhosphoSitePlus   Signor 10734310, 9890893
Q13480 (GAB1) Y472 HPRD   neXtProt   phospho.ELM   PhosphoSitePlus   Signor 10734310, 9890893
Q13480 (GAB1) Y589 HPRD   phospho.ELM   PhosphoSitePlus   Signor 10734310, 9890893
Q13480-2 (GAB1) Y619 HPRD   neXtProt 10734310, 9890893
Q13480 (GAB1) Y627 HPRD   phospho.ELM   PhosphoSitePlus   Signor 17016520, 10734310, 17389395, ...20068231, 9890893
Q13480-2 (GAB1) Y657 HPRD   neXtProt 17016520, 10734310, 17389395, ...20068231, 9890893
Q13480 (GAB1) Y659 HPRD   phospho.ELM   PhosphoSitePlus   Signor 16497976, 10734310, 18669648, ...17389395, 9890893
Q13480-2 (GAB1) Y689 HPRD   neXtProt 16497976, 10734310, 18669648, ...17389395, 9890893
Q14457 (BECN1) Y229 PhosphoSitePlus 24034250
Q14457 (BECN1) Y233 PhosphoSitePlus 24034250
Q14457 (BECN1) Y352 PhosphoSitePlus 24034250
Q15645 (TRIP13) Y56 Signor 32860853
Q38SD2 (LRRK1) Y971 neXtProt   PhosphoSitePlus 22337768
Q8IVM0 (CCDC50) Y217 neXtProt   PhosphoSitePlus   Signor 19059208
Q8IVM0 (CCDC50) Y279 neXtProt   PhosphoSitePlus   Signor 19059208
Q8IVM0 (CCDC50) Y304 neXtProt   PhosphoSitePlus   Signor 19059208
Q8NFJ5 (GPRC5A) Y317 PhosphoSitePlus 25311788
Q8NFJ5 (GPRC5A) Y320 PhosphoSitePlus 25311788
Q8NFJ5 (GPRC5A) Y347 PhosphoSitePlus 25311788
Q8NFJ5 (GPRC5A) Y350 PhosphoSitePlus 25311788
Q8TDY4 (ASAP3) Y34 PhosphoSitePlus   Signor 23776207
Q92529-2 (SHC3) Y218 neXtProt   PhosphoSitePlus 11791173
Q92529-2 (SHC3) Y219 neXtProt   PhosphoSitePlus 11791173
Q92529-2 (SHC3) Y256 neXtProt   PhosphoSitePlus 11791173
Q92529-2 (SHC3) Y257 neXtProt   PhosphoSitePlus 11791173
Q92529-2 (SHC3) Y283 neXtProt   PhosphoSitePlus 11791173
Q92529-2 (SHC3) Y301 neXtProt   PhosphoSitePlus 11791173
Q92952 (KCNN1) Y109 PhosphoSitePlus 23496660
Q96TA1 (NIBAN2) Y593 PhosphoSitePlus 26721396
Q9P0J1 (PDP1) Y381 PhosphoSitePlus 24486017
Q9UBN7 (HDAC6) Y570 neXtProt   PhosphoSitePlus   Signor 20029029
Q9UK17 (KCND3) Y136 PhosphoSitePlus 22198508
Q9UKV8 (AGO2) Y393 PhosphoSitePlus 23636329


Proteoforms

PRO ID (Short Label) Sites PTM Enzyme Source PMID
PR:000047261 (hEGFR/SigPep-/Phos:1) pY1092,pY1110,pY1172,pY1197 PRO
PR:000047262 (hEGFR/SigPep-/Phos:2) pY1016,pY1069,pY1092,pY1110,pY1172,pY1197 PRO
PR:000027479 (hEGFR/iso:1/SigPep-/Phos:1) pY869 PRO 18789131
PR:000049849 (hEGFR/SigPep-/Phos:3) pS1070,pS1071,pS1081,pS1166 PRO 10347170
PR:000049851 (hEGFR/SigPep-/Phos:4) pS768 PRO 10347170


PTM-dependent PPI

PTM type Substrate Site Interactant Association type Source PMID
Phosphorylation O43707 (ACTN4) Y31 P00533 (EGFR) unknown eFIP 33532643
Phosphorylation P00533 (EGFR) S1071 P22681 (CBL) increased_association eFIP 20877636
Phosphorylation P04626 (ERBB2) Y1248 P00533 (EGFR) unknown eFIP 15163624
Phosphorylation P04626 (ERBB2) T701 P00533 (EGFR) unknown eFIP 28632938
Phosphorylation P14618 (PKM) S37 P00533 (EGFR) unknown eFIP 23178880
Phosphorylation P15311 (EZR) Y146 P00533 (EGFR) unknown eFIP 26936397
Phosphorylation P29317 (EPHA2) S897 P00533 (EGFR) increased_association eFIP 35668076
Phosphorylation P35568 (IRS1) Y612 P00533 (EGFR) increased_association eFIP 17902048
Phosphorylation P35790 (CHKA) Y333 P00533 (EGFR) unknown eFIP 21822308
Phosphorylation P46108 (CRK) Y221 P00533 (EGFR) unknown eFIP 10595738
Phosphorylation P78527 (PRKDC) T2609 P00533 (EGFR) inhibited_association eFIP 22923485
Phosphorylation Q13547 (HDAC1) Y72 P00533 (EGFR) unknown eFIP 33976119
Phosphorylation Q9UJM3 (ERRFI1) Y394 P00533 (EGFR) unknown eFIP 26280531


Proteoform PPIs

Protein 1 Relation Protein 2 Source PMID
PR:000049849 (hEGFR/SigPep-/Phos:3) decreased Interaction PR:P00533 (hEGFR) PRO 10347170


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K37 N37 Biomuta DOID:3571 / liver cancer [ cosmic ]
Y117 C117 Biomuta DOID:3571 / liver cancer [ cosmic ]
N175 D175 Biomuta DOID:2531 / hematologic cancer [ cosmic ]
R222 C222 Biomuta DOID:4159 / skin cancer [ cosmic ] DOID:1319 / brain cancer [ cosmic, icgc, tcga ] DOID:9256 / colorectal cancer [ cosmic, icgc, tcga ]
R222 L222 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
R222 H222 Biomuta DOID:9256 / colorectal cancer [ cosmic ] DOID:1612 / breast cancer [ cosmic ]
R224 H224 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc ]
R224 C224 Biomuta DOID:2531 / hematologic cancer [ cosmic ]
S229 N229 Biomuta DOID:10283 / prostate cancer [ cosmic ]
S229 C229 Biomuta DOID:8618 / oral cavity cancer [ cosmic ] DOID:1319 / brain cancer [ cosmic, icgc, tcga ] DOID:1324 / lung cancer [ cosmic, icgc ] DOID:11934 / head and neck cancer [ icgc ]
C311 F311 Biomuta DOID:1324 / lung cancer [ cosmic ]
C311 S311 Biomuta DOID:1319 / brain cancer [ cosmic ]
C311 R311 Biomuta DOID:1319 / brain cancer [ cosmic ]
C311 * Biomuta DOID:9256 / colorectal cancer [ cosmic ]
C329 Y329 Biomuta DOID:4362 / cervical cancer [ icgc ]
T354 M354 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ]
S364 F364 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
S380 F380 Biomuta DOID:1319 / brain cancer [ cosmic, icgc ]
N413 K413 Biomuta DOID:1612 / breast cancer [ cosmic ]
T430 I430 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc ]
S437 Y437 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ] DOID:9256 / colorectal cancer [ cosmic ]
S442 R442 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S442 I442 Biomuta DOID:1324 / lung cancer [ cosmic ]
N444 I444 Biomuta DOID:1319 / brain cancer [ cosmic ]
N444 S444 Biomuta DOID:363 / uterine cancer [ icgc ]
S511 Y511 Biomuta DOID:11054 / urinary bladder cancer [ cosmic ]
N603 K603 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
N623 H623 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
N623 Y623 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S645 C645 Biomuta DOID:1319 / brain cancer [ cosmic, icgc, tcga ] DOID:1324 / lung cancer [ cosmic ]
S645 F645 Biomuta DOID:4159 / skin cancer [ cosmic ]
T678 M678 Biomuta DOID:363 / uterine cancer [ icgc ]
T693 A693 Biomuta DOID:1324 / lung cancer [ cosmic ]
S695 G695 Biomuta DOID:1781 / thyroid gland cancer [ cosmic ]
K708 R708 Biomuta DOID:2394 / ovarian cancer [ cosmic ]
K708 E708 Biomuta DOID:2394 / ovarian cancer [ cosmic ] DOID:2531 / hematologic cancer [ cosmic ]
K708 M708 Biomuta DOID:1324 / lung cancer [ cosmic ]
K714 N714 Biomuta DOID:1319 / brain cancer [ cosmic, icgc ] DOID:1324 / lung cancer [ cosmic ]
K714 E714 Biomuta DOID:1324 / lung cancer [ cosmic ]
K714 T714 Biomuta DOID:5041 / esophageal cancer [ cosmic ]
K716 R716 Biomuta DOID:2394 / ovarian cancer [ cosmic, icgc ]
K716 E716 Biomuta DOID:10534 / stomach cancer [ cosmic ]
S720 P720 Biomuta DOID:1324 / lung cancer [ cosmic ]
S720 T720 Biomuta DOID:1324 / lung cancer [ cosmic ]
S720 C720 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
S720 F720 Biomuta DOID:4159 / skin cancer [ cosmic ] DOID:2394 / ovarian cancer [ cosmic ] DOID:3571 / liver cancer [ cosmic ] DOID:1324 / lung cancer [ cosmic ]
T725 A725 Biomuta DOID:2394 / ovarian cancer [ cosmic ]
T725 M725 Biomuta DOID:4606 / bile duct cancer [ cosmic ] DOID:5158 / pleural cancer [ cosmic ] DOID:1324 / lung cancer [ cosmic ] DOID:2394 / ovarian cancer [ cosmic ] DOID:5041 / esophageal cancer [ cosmic ] DOID:1319 / brain cancer [ cosmic ]
Y727 C727 Biomuta DOID:9253 / gastrointestinal stromal tumor [ cosmic ] DOID:1324 / lung cancer [ cosmic ]
K728 * Biomuta DOID:1324 / lung cancer [ cosmic ]
K737 E737 Biomuta DOID:4159 / skin cancer [ cosmic, icgc, tcga ]
K737 R737 Biomuta DOID:1324 / lung cancer [ cosmic ]
K745 R745 Biomuta DOID:8618 / oral cavity cancer [ cosmic ]
K745 T745 Biomuta DOID:1324 / lung cancer [ cosmic ]
S752 F752 Biomuta DOID:1324 / lung cancer [ cosmic ]
S752 Y752 Biomuta DOID:1324 / lung cancer [ cosmic ]
S752 P752 Biomuta DOID:8618 / oral cavity cancer [ cosmic ] DOID:1781 / thyroid gland cancer [ cosmic ]
K754 I754 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
K754 E754 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
K754 R754 Biomuta DOID:1324 / lung cancer [ cosmic ]
K754 A754 Biomuta DOID:1324 / lung cancer [ cosmic ]
K757 R757 Biomuta DOID:4606 / bile duct cancer [ cosmic ] DOID:1324 / lung cancer [ civic, cosmic ]
K757 M757 Biomuta DOID:1324 / lung cancer [ cosmic ]
S768 G768 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S768 N768 Biomuta DOID:1324 / lung cancer [ cosmic ]
S768 I768 Biomuta DOID:1612 / breast cancer [ cosmic, icgc ] DOID:1324 / lung cancer [ civic, cosmic, icgc ] DOID:10283 / prostate cancer [ cosmic ] DOID:5041 / esophageal cancer [ cosmic ] DOID:3953 / adrenal gland cancer [ cosmic ] DOID:1319 / brain cancer [ cosmic ]
S768 T768 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
T790 M790 Biomuta [ cosmic ] DOID:4606 / bile duct cancer [ cosmic ] DOID:1324 / lung cancer [ civic, cosmic, icgc ] DOID:1612 / breast cancer [ cosmic ] DOID:1793 / pancreatic cancer [ civic ] DOID:9256 / colorectal cancer [ cosmic ] DOID:8618 / oral cavity cancer [ cosmic ] DOID:1319 / brain cancer [ cosmic ]
T790 A790 Biomuta DOID:5041 / esophageal cancer [ cosmic ]
T790 S790 Biomuta DOID:2531 / hematologic cancer [ cosmic ]
Y801 H801 Biomuta DOID:8618 / oral cavity cancer [ cosmic ] DOID:1725 / peritoneum cancer [ cosmic ]
Y801 C801 Biomuta DOID:10534 / stomach cancer [ cosmic ] DOID:1324 / lung cancer [ cosmic ]
Y827 * Biomuta DOID:363 / uterine cancer [ cosmic ]
V845 E845 Biomuta DOID:2394 / ovarian cancer [ cosmic ]
V845 A845 Biomuta DOID:1324 / lung cancer [ cosmic ]
V845 M845 Biomuta DOID:3953 / adrenal gland cancer [ cosmic ] DOID:1324 / lung cancer [ cosmic ]
K846 R846 Biomuta DOID:1324 / lung cancer [ cosmic ]
K852 N852 Biomuta DOID:2394 / ovarian cancer [ cosmic ]
K852 T852 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
K852 R852 Biomuta DOID:1324 / lung cancer [ cosmic ]
K860 I860 Biomuta DOID:1612 / breast cancer [ cosmic ] DOID:5041 / esophageal cancer [ cosmic ] DOID:1324 / lung cancer [ cosmic ]
K867 T867 Biomuta DOID:1324 / lung cancer [ cosmic ]
Y869 C869 Biomuta DOID:1319 / brain cancer [ cosmic ] DOID:11054 / urinary bladder cancer [ cosmic ]
K875 R875 Biomuta DOID:11054 / urinary bladder cancer [ cosmic ]
Y891 C891 Biomuta DOID:1319 / brain cancer [ cosmic, icgc ]
Y915 C915 Biomuta DOID:5041 / esophageal cancer [ cosmic ]
Y915 H915 Biomuta DOID:2531 / hematologic cancer [ cosmic ]
T940 A940 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
Y944 C944 Biomuta DOID:10534 / stomach cancer [ cosmic ]
Y1016 N1016 Biomuta DOID:1324 / lung cancer [ cosmic ]
S1028 L1028 Biomuta DOID:4159 / skin cancer [ cosmic ]
T1032 S1032 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ]
S1036 R1036 Biomuta DOID:1319 / brain cancer [ cosmic, icgc ]
T1041 A1041 Biomuta DOID:1612 / breast cancer [ cosmic ]
S1042 N1042 Biomuta DOID:263 / kidney cancer [ cosmic, icgc ]
S1045 F1045 Biomuta [ cosmic ] DOID:10283 / prostate cancer [ cosmic ] DOID:4159 / skin cancer [ cosmic ] DOID:9256 / colorectal cancer [ cosmic ]
S1064 R1064 Biomuta DOID:10534 / stomach cancer [ cosmic ]
S1064 N1064 Biomuta [ cosmic ]
S1064 G1064 Biomuta DOID:1612 / breast cancer [ cosmic ]
Y1069 C1069 Biomuta DOID:9256 / colorectal cancer [ cosmic ] DOID:4606 / bile duct cancer [ cosmic ]
S1070 T1070 Biomuta DOID:1324 / lung cancer [ cosmic ]
T1078 I1078 Biomuta DOID:4159 / skin cancer [ cosmic ]
S1096 F1096 Biomuta DOID:8618 / oral cavity cancer [ cosmic ] DOID:9256 / colorectal cancer [ cosmic, icgc ]
Y1110 F1110 Biomuta DOID:4159 / skin cancer [ cosmic ]
S1120 N1120 Biomuta [ cosmic ]
S1130 G1130 Biomuta DOID:1324 / lung cancer [ cosmic ]
S1130 R1130 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
Y1138 C1138 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
T1150 S1150 Biomuta DOID:3571 / liver cancer [ cosmic, icgc ]
S1153 I1153 Biomuta DOID:3571 / liver cancer [ cosmic ] DOID:5041 / esophageal cancer [ cosmic ]
S1153 N1153 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
S1162 C1162 Biomuta DOID:3571 / liver cancer [ cosmic, icgc ]
S1162 N1162 Biomuta DOID:1319 / brain cancer [ cosmic ]
K1182 N1182 Biomuta [ cosmic ] DOID:1115 / sarcoma [ icgc ]
K1188 * Biomuta DOID:2531 / hematologic cancer [ cosmic ]
K1188 E1188 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
K1188 T1188 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S1190 P1190 Biomuta DOID:10283 / prostate cancer [ cosmic ]
Y1197 C1197 Biomuta DOID:10534 / stomach cancer [ cosmic ]
R1199 M1199 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
R1199 T1199 Biomuta DOID:263 / kidney cancer [ cosmic ]