Protein Information

Cytoscape View

UniProt AC / UniProt ID P00523 / SRC_CHICK
Protein Name Proto-oncogene tyrosine-protein kinase Src
Gene Name Name: SRC
Organism Gallus gallus (Chicken)

PRO ID PR:P00523
DAG View
PRO Name proto-oncogene tyrosine-protein kinase Src (chicken)
Definition A proto-oncogene tyrosine-protein kinase Src that is encoded in the genome of chicken.
Short Label chick-SRC
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species

P00523 (SRC) as Substrate

Site PTM Type PTM Enzyme Score Source PMID
S12 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 2996780
S17 Phosphorylation phospho.ELM   PhosphoSitePlus   RLIMS-P 2423705, 2454397
T34 Phosphorylation phospho.ELM   PhosphoSitePlus   RLIMS-P   UniProt 2470512, 1956339
T46 Phosphorylation phospho.ELM   PhosphoSitePlus   RLIMS-P   UniProt 2470512, 1956339
S48 Phosphorylation phospho.ELM   PhosphoSitePlus
S72 Phosphorylation phospho.ELM   PhosphoSitePlus   RLIMS-P   UniProt 2470512, 1956339
Y416 Phosphorylation P00523 (SRC) phospho.ELM   PhosphoSitePlus   RLIMS-P   UniProt 7687537, 2452399, 8856081, ...6273838
Y436 Phosphorylation P00523 (SRC) UniProt 8856081
Y519 Phosphorylation PhosphoSitePlus
Y527 Phosphorylation IntAct   phospho.ELM   PhosphoSitePlus   RLIMS-P   UniProt 2441875, 9108021, 10339427, ...7688738, 11035913, 2452399, 19888460, 2420005, 11923305

P00523 (SRC) as PTM Enzyme

Substrate Site Score Source PMID
P00523 (SRC) Y416 phospho.ELM   PhosphoSitePlus   UniProt 7687537, 6273838
P00523 (SRC) Y436 UniProt 8856081
P05625 (RAF1) Y340 PhosphoSitePlus 12843393
P05625 (RAF1) Y341 PhosphoSitePlus 12843393
P17785 (ANXA2) Y24 phospho.ELM 2143014
P49024 (PXN) Y31 PhosphoSitePlus 11695992
P49024 (PXN) Y40 PhosphoSitePlus 11695992
P49024 (PXN) Y88 PhosphoSitePlus 11695992
Q00944 (PTK2) Y576 PhosphoSitePlus 9790958
Q00944 (PTK2) Y926 PhosphoSitePlus 15130480
Q01406 (CTTN1) Y430 phospho.ELM 8578591
Q01406 (CTTN1) Y477 phospho.ELM 8578591
Q01406 (CTTN1) Y483 phospho.ELM 8578591
Q01406 (CTTN1) Y499 phospho.ELM 8578591
Q9PUM6 (CACHA1B) Y804 PhosphoSitePlus 15536086
Q9PUM6 (CACHA1B) Y815 PhosphoSitePlus 15536086

PTM-dependent PPI

PTM type Substrate Site Interactant Association type Source PMID
Phosphorylation P00523 (SRC) Y527 P18433 (PTPRA) unknown eFIP 11923305
Phosphorylation P03372 (ESR1) Y537 P00523 (SRC) unknown eFIP 11032808
Phosphorylation P15311 (EZR) Y191 P00523 (SRC) unknown eFIP 15647376
Phosphorylation P18052 (Ptpra) Y825 P00523 (SRC) unknown eFIP 12834342
Phosphorylation P18433 (PTPRA) Y798 P00523 (SRC) unknown eFIP 10698938
Phosphorylation Q07954 (LRP1) Y4507 P00523 (SRC) unknown eFIP 21968187
Phosphorylation Q8IZP0 (ABI1) Y421 P00523 (SRC) unknown eFIP 20598684
Phosphorylation Q90738 (AFAP1) Y453 P00523 (SRC) unknown eFIP 9655255

Proteoform PPIs

Protein 1 Relation Protein 2 Source PMID
PR:000036590 (hEZR/iso:1/Phos:3) Interaction PR:P00523-1 (chick-SRC/iso:1) PRO 15647376