iPTMnet Report P00517 PRKACA

Protein Information

Cytoscape View

UniProt AC / UniProt ID	P00517 / KAPCA_BOVIN
Protein Name	cAMP-dependent protein kinase catalytic subunit alpha
Gene Name	Name: PRKACA
Organism	Bos taurus (Bovine)

PRO ID	PR:P00517 DAG View
PRO Name	cAMP-dependent protein kinase catalytic subunit alpha (cow)
Definition	A cAMP-dependent protein kinase catalytic subunit alpha that is encoded in the genome of cow.
Short Label	cow-PRKACA
Category	organism-gene

Interactive Sequence View

	Select/align proteoforms across species

P00517 (PRKACA) as Substrate

Expanded View

	Site	PTM Type	PTM Enzyme	Score	Source	PMID
	G2	Myristoylation		score2	UniProt	6262777
	S11	Phosphorylation		score3	phospho.ELM PhosphoSitePlus	8395513
	S15	Phosphorylation		score1	PhosphoSitePlus
	T49	Phosphorylation		score1	PhosphoSitePlus
	S54	Phosphorylation		score1	PhosphoSitePlus
	S140	Phosphorylation		score3	phospho.ELM PhosphoSitePlus	8395513
	T198	Phosphorylation		score4	phospho.ELM PhosphoSitePlus UniProt	221492, 6262777
	S213	Phosphorylation		score1	PhosphoSitePlus
	S260	Phosphorylation		score1	PhosphoSitePlus
	S326	Phosphorylation		score1	PhosphoSitePlus
	S339	Phosphorylation		score3	phospho.ELM PhosphoSitePlus UniProt	6262777

	Site	PTM Type	PTM Enzyme	Score	Source	PMID
	S11	Phosphorylation		score2	PRO	14656443
	T198	Phosphorylation		score2	PRO	14656443
	S339	Phosphorylation		score2	PRO	14656443

P00517 (PRKACA) as PTM Enzyme

Protein as Phosphorylation Enzyme

	Substrate	Site	Score	Source	PMID
	P00515 (PRKAR2A)	S96	score3	PhosphoSitePlus	6293815, 6247212
	P02253 (H1-2)	S36	score3	PhosphoSitePlus	199593, 185207
	P02522 (CRYBB2)	S204	score2	PhosphoSitePlus	3107907
	P04972 (PDE6G)	T35	score2	PhosphoSitePlus	11741972
	P06624 (MIP)	S243	score2	PhosphoSitePlus	2176601
	P07516 (PPP1R1B)	T34	score2	PhosphoSitePlus	2557337
	P08057 (TNNI3)	S24	score3	PhosphoSitePlus RLIMS-P+	2373082
	P08057 (TNNI3)	S25	score3	PhosphoSitePlus RLIMS-P+	2373082
	P17289 (TH)	S40	score2	PhosphoSitePlus	11359875
	P19632 (PDC)	S73	score2	PhosphoSitePlus	2394752
	P26285 (PFKFB2)	S467	score3	PhosphoSitePlus	2846551, 9211863
	P26285 (PFKFB2)	S484	score2	PhosphoSitePlus	9211863
	P29473 (NOS3)	S1179	score2	PhosphoSitePlus	15383526
	P51177 (GUCA1B)	S201	score2	PhosphoSitePlus	15448139
	Q9MZ06 (FGFBP1)	S36	score2	PhosphoSitePlus	17560725

Proteoforms

	PRO ID (Short Label)	Sites	PTM Enzyme	Source	PMID
	PR:000025887 (cow-PRKACA/iso:1/InitMet-/Phos:1)	pS11,pT198,pS339		PRO	14656443