Protein Information

Cytoscape View


UniProt AC / UniProt ID O96004 / HAND1_HUMAN
Protein Name Heart- and neural crest derivatives-expressed protein 1
Gene Name Name: HAND1
Synonyms:BHLHA27,EHAND;
Organism Homo sapiens (Human)

PRO ID PR:O96004
DAG View
PRO Name heart- and neural crest derivatives-expressed protein 1 (human)
Definition A heart- and neural crest derivatives-expressed protein 1 that is encoded in the genome of human.
Short Label hHAND1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


O96004 (HAND1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S98 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   Signor 14636580
S98 Phosphorylation P17252 (PRKCA) HPRD   Signor 14636580
S98 Phosphorylation P17612 (PRKACA) HPRD 14636580
T107 Phosphorylation HPRD   neXtProt   phospho.ELM   RLIMS-P   Signor 15188014, 17891141, 14636580, ...15103396
T107 Phosphorylation O00444 (PLK4) neXtProt 17891141
T107 Phosphorylation P17252 (PRKCA) HPRD   Signor 14636580
T107 Phosphorylation P17612 (PRKACA) HPRD 14636580
S109 Phosphorylation HPRD   neXtProt   phospho.ELM   RLIMS-P   Signor 15188014, 17891141, 14636580, ...15103396
S109 Phosphorylation O00444 (PLK4) neXtProt 17891141
S109 Phosphorylation P17252 (PRKCA) HPRD   Signor 14636580
S109 Phosphorylation P17612 (PRKACA) HPRD 14636580


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S109 N109 Biomuta DOID:9256 / colorectal cancer [ tcga ]