iPTMnet Report for O95996 (APC2)


Protein Information

Cytoscape View


UniProt AC / UniProt ID O95996 / APCL_HUMAN
Protein Name Adenomatous polyposis coli protein 2
Gene Name Name: APC2
Synonyms:APCL;
Organism Homo sapiens (Human)

PRO ID PR:O95996
DAG View
PRO Name adenomatous polyposis coli protein 2 (human)
Definition An adenomatous polyposis coli protein 2 that is encoded in the genome of human.
Short Label hAPC2
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


O95996 (APC2) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S4 O-Glycosylation GlyGen 31492838
S108 Phosphorylation PhosphoSitePlus
S113 Phosphorylation PhosphoSitePlus
S116 Phosphorylation PhosphoSitePlus
S304 Phosphorylation PhosphoSitePlus
S510 Phosphorylation PhosphoSitePlus
S511 Phosphorylation PhosphoSitePlus
S517 Phosphorylation PhosphoSitePlus
S678 Phosphorylation PhosphoSitePlus
S873 Phosphorylation PhosphoSitePlus
S875 Phosphorylation PhosphoSitePlus
S876 Phosphorylation PhosphoSitePlus
S952 Phosphorylation IEDB 35494241
T998 Phosphorylation PhosphoSitePlus
Y999 Phosphorylation PhosphoSitePlus
S1052 Phosphorylation PhosphoSitePlus
S1068 Phosphorylation PhosphoSitePlus
S1148 Phosphorylation PhosphoSitePlus
S1160 Phosphorylation PhosphoSitePlus
S1164 Phosphorylation PhosphoSitePlus
S1167 Phosphorylation PhosphoSitePlus
R1427 Methylation PhosphoSitePlus
R1431 Methylation PhosphoSitePlus
S1455 O-Glycosylation GlyGen 25813380
S1675 Phosphorylation PhosphoSitePlus
S1834 Phosphorylation PhosphoSitePlus
S1861 Phosphorylation PhosphoSitePlus
T1863 Phosphorylation PhosphoSitePlus
S1883 Phosphorylation PhosphoSitePlus
S2009 Phosphorylation PhosphoSitePlus
S2016 Phosphorylation PhosphoSitePlus
S2025 Phosphorylation PhosphoSitePlus
S2041 Phosphorylation PhosphoSitePlus
S2101 Phosphorylation PhosphoSitePlus
S2203 Phosphorylation PhosphoSitePlus
S2204 Phosphorylation PhosphoSitePlus
T2205 Phosphorylation PhosphoSitePlus
S2206 Phosphorylation PhosphoSitePlus
T2211 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S1675 Phosphorylation HPRD 19413330


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S952 L952 Biomuta DOID:8618 / oral cavity cancer [ cosmic ] DOID:11054 / urinary bladder cancer [ cosmic, icgc ]
Y999 * Biomuta DOID:4159 / skin cancer [ cosmic ] DOID:10283 / prostate cancer [ cosmic ]
R1431 H1431 Biomuta DOID:2531 / hematologic cancer [ cosmic ]
R1431 C1431 Biomuta DOID:9253 / gastrointestinal stromal tumor [ cosmic ]