iPTMnet Report for O95994 (AGR2)


Protein Information

Cytoscape View


UniProt AC / UniProt ID O95994 / AGR2_HUMAN
Protein Name Anterior gradient protein 2 homolog precursor
Gene Name Name: AGR2
Synonyms:AG2;ORFNames:UNQ515/PRO1030;
Organism Homo sapiens (Human)

PRO ID PR:O95994
DAG View
PRO Name anterior gradient protein 2 homolog (human)
Definition An anterior gradient protein 2 that is encoded in the genome of human.
Short Label hAGR2
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


O95994 (AGR2) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S36 Phosphorylation PhosphoSitePlus
K88 Acetylation PhosphoSitePlus
K89 Acetylation PhosphoSitePlus
K89 Ubiquitination PhosphoSitePlus
Y111 Phosphorylation PhosphoSitePlus
T113 Phosphorylation PhosphoSitePlus
T114 Phosphorylation PhosphoSitePlus
K116 Acetylation PhosphoSitePlus
S119 Phosphorylation PhosphoSitePlus
Y124 Phosphorylation PhosphoSitePlus
S146 Phosphorylation PhosphoSitePlus
Y150 Phosphorylation PhosphoSitePlus
Y152 Phosphorylation PhosphoSitePlus
T157 Phosphorylation PhosphoSitePlus
K165 Acetylation PhosphoSitePlus
K166 Acetylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S36 F36 Biomuta DOID:11054 / urinary bladder cancer [ cosmic, icgc ]
K88 N88 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ] DOID:1319 / brain cancer [ cosmic, icgc ]
Y111 H111 Biomuta DOID:263 / kidney cancer [ cosmic, icgc ]
T114 I114 Biomuta DOID:1319 / brain cancer [ cosmic ]
K116 R116 Biomuta DOID:1324 / lung cancer [ cosmic ]
K165 R165 Biomuta DOID:3571 / liver cancer [ cosmic, icgc ]
K166 T166 Biomuta DOID:9256 / colorectal cancer [ cosmic ]