iPTMnet Report for O95954 (FTCD)


Protein Information

Cytoscape View


UniProt AC / UniProt ID O95954 / FTCD_HUMAN
Protein Name Formimidoyltransferase-cyclodeaminase
Gene Name Name: FTCD
Organism Homo sapiens (Human)

PRO ID PR:O95954
DAG View
PRO Name formimidoyltransferase-cyclodeaminase (human)
Definition A formimidoyltransferase-cyclodeaminase that is encoded in the genome of human.
Short Label hFTCD
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


O95954 (FTCD) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
Y124 Phosphorylation PhosphoSitePlus
Y146 Phosphorylation PhosphoSitePlus
Y225 Phosphorylation PhosphoSitePlus
Y250 Phosphorylation PhosphoSitePlus
S316 Phosphorylation PhosphoSitePlus   UniProt 24275569
Y324 Phosphorylation PhosphoSitePlus
S358 Phosphorylation PhosphoSitePlus
R381 Methylation PhosphoSitePlus
S386 Phosphorylation PhosphoSitePlus   UniProt 24275569
R399 Methylation PhosphoSitePlus
S402 Phosphorylation PhosphoSitePlus
R424 Methylation PhosphoSitePlus
R436 Methylation PhosphoSitePlus
R445 Methylation PhosphoSitePlus
S449 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S549 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
Y124 H124 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
Y225 H225 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ]
Y225 C225 Biomuta DOID:363 / uterine cancer [ icgc ]
S358 L358 Biomuta DOID:4159 / skin cancer [ cosmic ]
R381 W381 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
R399 C399 Biomuta DOID:4159 / skin cancer [ cosmic ]
S402 L402 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
R424 M424 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
R436 H436 Biomuta DOID:363 / uterine cancer [ icgc ]