iPTMnet Report for O95936 (EOMES)


Protein Information

Cytoscape View


UniProt AC / UniProt ID O95936 / EOMES_HUMAN
Protein Name Eomesodermin homolog
Gene Name Name: EOMES
Synonyms:TBR2;
Organism Homo sapiens (Human)

PRO ID PR:O95936
DAG View
PRO Name eomesodermin homolog (human)
Definition An eomesodermin that is encoded in the genome of human.
Short Label hEOMES
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


O95936 (EOMES) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S42 Phosphorylation PhosphoSitePlus
S107 Phosphorylation PhosphoSitePlus
S116 Phosphorylation PhosphoSitePlus
S148 Phosphorylation PhosphoSitePlus
C160 Methylation IEDB 31844290
S216 Phosphorylation PhosphoSitePlus
S221 Phosphorylation PhosphoSitePlus
K291 Ubiquitination PhosphoSitePlus
T385 Phosphorylation PhosphoSitePlus
R578 Methylation PhosphoSitePlus
R583 Methylation PhosphoSitePlus
S596 Phosphorylation PhosphoSitePlus
T621 Phosphorylation PhosphoSitePlus
S627 Phosphorylation PhosphoSitePlus
S646 Phosphorylation PhosphoSitePlus   RLIMS-P 30705751
S648 Phosphorylation PhosphoSitePlus
S657 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
T176 Phosphorylation PhosphoSitePlus
S178 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
T385 N385 Biomuta DOID:10283 / prostate cancer [ cosmic ]
R578 * Biomuta DOID:9256 / colorectal cancer [ cosmic ]
R578 P578 Biomuta DOID:10534 / stomach cancer [ cosmic ]
R578 Q578 Biomuta DOID:4362 / cervical cancer [ icgc ] DOID:5041 / esophageal cancer [ cosmic ]
T621 A621 Biomuta DOID:4362 / cervical cancer [ icgc ]
S627 Y627 Biomuta DOID:363 / uterine cancer [ icgc ]
S627 F627 Biomuta DOID:363 / uterine cancer [ cosmic, icgc, tcga ]
S657 P657 Biomuta DOID:10534 / stomach cancer [ cosmic ]