iPTMnet Report for O95922 (TTLL1)


Protein Information

Cytoscape View


UniProt AC / UniProt ID O95922 / TTLL1_HUMAN
Protein Name Polyglutamylase complex subunit TTLL1
Gene Name Name: TTLL1
Synonyms:C22orf7;
Organism Homo sapiens (Human)

PRO ID PR:O95922
DAG View
PRO Name polyglutamylase complex subunit TTLL1 (human)
Definition A polyglutamylase complex subunit TTLL1 that is encoded in the genome of human.
Short Label hTTLL1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


O95922 (TTLL1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
T9 O-Glycosylation GlyGen 31492838
K146 Ubiquitination PhosphoSitePlus
K165 Ubiquitination PhosphoSitePlus
S171 Phosphorylation PhosphoSitePlus
S173 Phosphorylation PhosphoSitePlus
Y178 Phosphorylation PhosphoSitePlus
S181 Phosphorylation PhosphoSitePlus
Y183 Phosphorylation PhosphoSitePlus
Y200 Phosphorylation PhosphoSitePlus
Y206 Phosphorylation PhosphoSitePlus
Y212 Phosphorylation PhosphoSitePlus
Y214 Phosphorylation PhosphoSitePlus
Y268 Phosphorylation PhosphoSitePlus
S279 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K165 N165 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S173 Y173 Biomuta DOID:10283 / prostate cancer [ cosmic ]
S173 F173 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
S181 P181 Biomuta DOID:10534 / stomach cancer [ cosmic ]
Y206 C206 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]