iPTMnet Report for O95905 (ECD)


Protein Information

Cytoscape View


UniProt AC / UniProt ID O95905 / ECD_HUMAN
Protein Name Protein ecdysoneless homolog
Gene Name Name: ECD
Organism Homo sapiens (Human)

PRO ID PR:O95905
DAG View
PRO Name protein ecdysoneless homolog (human)
Definition A protein ecdysoneless that is encoded in the genome of human.
Short Label hECD
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


O95905 (ECD) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K32 Ubiquitination PhosphoSitePlus
K68 Ubiquitination PhosphoSitePlus
K100 Ubiquitination PhosphoSitePlus
C141 Methylation IEDB 31844290
K153 Ubiquitination PhosphoSitePlus
S154 Phosphorylation PhosphoSitePlus
T163 Phosphorylation PhosphoSitePlus
S178 Phosphorylation PhosphoSitePlus
S184 Phosphorylation PhosphoSitePlus
S186 Phosphorylation PhosphoSitePlus
K201 Ubiquitination PhosphoSitePlus
S205 Phosphorylation PhosphoSitePlus
C211 Methylation IEDB 31844290
K222 Acetylation PhosphoSitePlus
C246 Methylation IEDB 31844290
K250 Ubiquitination PhosphoSitePlus
K303 Ubiquitination PhosphoSitePlus
K314 Ubiquitination PhosphoSitePlus
K323 Ubiquitination PhosphoSitePlus
S325 Phosphorylation PhosphoSitePlus
S339 Phosphorylation PhosphoSitePlus
K347 Ubiquitination PhosphoSitePlus
K402 Ubiquitination PhosphoSitePlus
S419 Phosphorylation PhosphoSitePlus
K433 Ubiquitination PhosphoSitePlus
K444 Ubiquitination PhosphoSitePlus
Y448 Phosphorylation PhosphoSitePlus
S454 Phosphorylation PhosphoSitePlus
S456 Phosphorylation PhosphoSitePlus
K458 Ubiquitination PhosphoSitePlus
K463 Ubiquitination PhosphoSitePlus
K468 Ubiquitination PhosphoSitePlus
S477 Phosphorylation PhosphoSitePlus
S503 Phosphorylation P68400 (CSNK2A1) phospho.ELM   PhosphoSitePlus   UniProt 26711270, 18669648
S505 Phosphorylation P68400 (CSNK2A1) phospho.ELM   PhosphoSitePlus   UniProt 26711270, 18669648
S518 Phosphorylation P68400 (CSNK2A1) phospho.ELM   PhosphoSitePlus   UniProt 26711270, 18669648, 17081983
S534 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
K543 Ubiquitination PhosphoSitePlus
C557 Methylation IEDB 31844290
K560 Ubiquitination PhosphoSitePlus
S561 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
Y16 Phosphorylation HPRD 20068231
T162 Phosphorylation HPRD 20068231
S186 Phosphorylation HPRD 20068231
S325 Phosphorylation HPRD 20068231
S335 Phosphorylation HPRD 20068231
S339 Phosphorylation HPRD 20068231
S503 Phosphorylation HPRD 18669648, 17081983
S505 Phosphorylation HPRD 18669648, 17081983
S518 Phosphorylation HPRD 18669648, 17081983
S534 Phosphorylation HPRD 18669648
Site PTM Type PTM Enzyme Score Source PMID
T405 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S325 F325 Biomuta DOID:8618 / oral cavity cancer [ cosmic ] DOID:3571 / liver cancer [ cosmic ]
K347 M347 Biomuta DOID:363 / uterine cancer [ icgc ]
K444 N444 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
S503 * Biomuta DOID:3571 / liver cancer [ cosmic ]
S518 C518 Biomuta DOID:1324 / lung cancer [ cosmic ]
S534 F534 Biomuta DOID:4362 / cervical cancer [ cosmic, icgc ]
K560 N560 Biomuta DOID:263 / kidney cancer [ cosmic, icgc ]