Protein Information

Cytoscape View

UniProt AC / UniProt ID O95881 / TXD12_HUMAN
Protein Name Thioredoxin domain-containing protein 12 precursor
Gene Name Name: TXNDC12
Organism Homo sapiens (Human)

PRO ID PR:O95881
DAG View
PRO Name thioredoxin domain-containing protein 12 (human)
Definition A thioredoxin domain-containing protein 12 that is encoded in the genome of human.
Short Label hTXNDC12
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species

O95881 (TXNDC12) as Substrate

Site PTM Type PTM Enzyme Score Source PMID
S64 Phosphorylation PhosphoSitePlus
S121 Phosphorylation PhosphoSitePlus
K123 Ubiquitination PhosphoSitePlus
S136 O-Glycosylation GlyGen 21740066, 29237092, 29351928
K165 Acetylation PhosphoSitePlus

PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S136 I136 Biomuta DOID:1324 / lung cancer [ cosmic, icgc, tcga ]
K165 R165 Biomuta DOID:263 / kidney cancer [ tcga ]