iPTMnet Report for O95881 (TXNDC12)


Protein Information

Cytoscape View


UniProt AC / UniProt ID O95881 / TXD12_HUMAN
Protein Name Thioredoxin domain-containing protein 12 precursor
Gene Name Name: TXNDC12
Synonyms:TLP19;ORFNames:UNQ713/PRO1376;
Organism Homo sapiens (Human)

PRO ID PR:O95881
DAG View
PRO Name thioredoxin domain-containing protein 12 (human)
Definition A thioredoxin domain-containing protein 12 that is encoded in the genome of human.
Short Label hTXNDC12
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


O95881 (TXNDC12) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
C11 Methylation IEDB 31844290
S64 Phosphorylation PhosphoSitePlus
S121 Phosphorylation PhosphoSitePlus
K123 Ubiquitination PhosphoSitePlus
S136 O-Glycosylation GlyGen 31492838, 29351928, 21740066, ...29237092, 35254053
K165 Acetylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S136 I136 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
K165 R165 Biomuta DOID:263 / kidney cancer [ cosmic, icgc ]