Protein Information

Cytoscape View

UniProt AC / UniProt ID O95816 / BAG2_HUMAN
Protein Name BAG family molecular chaperone regulator 2
Gene Name Name: BAG2
Organism Homo sapiens (Human)

PRO ID PR:O95816
DAG View
PRO Name BAG family molecular chaperone regulator 2 (human)
Definition A BAG family molecular chaperone regulator 2 that is encoded in the genome of human.
Short Label hBAG2
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species

O95816 (BAG2) as Substrate

Site PTM Type PTM Enzyme Score Source PMID
A2 Acetylation UniProt 22814378
K5 Ubiquitination PhosphoSitePlus
K9 Ubiquitination PhosphoSitePlus
S20 Phosphorylation P49137 (MAPKAPK2) neXtProt   phospho.ELM   PhosphoSitePlus   RLIMS-P   Signor   UniProt 15271996, 20068231
S31 Phosphorylation PhosphoSitePlus   UniProt 23186163
S73 Phosphorylation PhosphoSitePlus   UniProt 18691976, 23186163
K111 Acetylation PhosphoSitePlus
K111 Ubiquitination PhosphoSitePlus
K123 Ubiquitination PhosphoSitePlus
S133 Phosphorylation PhosphoSitePlus
S137 Phosphorylation PhosphoSitePlus
Y139 Phosphorylation PhosphoSitePlus
S140 Phosphorylation PhosphoSitePlus
S143 Phosphorylation PhosphoSitePlus
S144 Phosphorylation PhosphoSitePlus
K154 Ubiquitination PhosphoSitePlus
C162 S-Nitrosylation dbSNO 19483679
K168 Acetylation PhosphoSitePlus
K168 Ubiquitination PhosphoSitePlus
K169 Acetylation PhosphoSitePlus
T176 Phosphorylation PhosphoSitePlus
K186 Acetylation PhosphoSitePlus
K186 Ubiquitination PhosphoSitePlus
K189 Ubiquitination PhosphoSitePlus
K195 Ubiquitination PhosphoSitePlus
K200 Ubiquitination PhosphoSitePlus
T201 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S20 Phosphorylation P49137 (MAPKAPK2) HPRD 19651622, 15271996, 20068231
S73 Phosphorylation HPRD 18691976
S133 Phosphorylation HPRD 20068231
S137 Phosphorylation HPRD 20068231
Y139 Phosphorylation HPRD 20068231
S140 Phosphorylation HPRD 20068231
S143 Phosphorylation HPRD 20068231
S144 Phosphorylation HPRD 20068231

PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K123 T123 Biomuta DOID:1909 / melanoma [ cosmic ]
S133 R133 Biomuta DOID:11934 / head and neck cancer [ tcga ]
Y139 * Biomuta DOID:3277 / thymus cancer [ tcga ]
S144 C144 Biomuta DOID:1612 / breast cancer [ cosmic, icgc, tcga ]
K168 N168 Biomuta DOID:363 / uterine cancer [ cosmic, icgc, tcga ] DOID:1612 / breast cancer [ tcga ]